RXR beta Activators
Items 1 to 10 of 15 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bexarotene | 153559-49-0 | sc-217753 sc-217753A | 10 mg 100 mg | $55.00 $250.00 | 6 | |
Bexarotene functions as a selective RXR beta agonist, distinguished by its unique ability to stabilize receptor dimers through specific ligand-receptor interactions. Its molecular design promotes effective docking within the ligand-binding domain, enhancing receptor activation. The compound's unique stereochemistry contributes to its selective affinity, while its dynamic solubility profile allows for versatile interactions within lipid environments, potentially influencing cellular signaling pathways and transcriptional regulation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
This compound is a metabolite of Vitamin A and plays a key role in mediating the functions of retinoids, potentially increasing RXRβ expression. | ||||||
LG 100268 | 153559-76-3 | sc-211737 | 5 mg | $390.00 | 2 | |
LG 100268 acts as a selective RXR beta agonist, characterized by its ability to modulate gene expression through distinct receptor conformational changes. Its unique binding affinity facilitates the formation of stable heterodimers with other nuclear receptors, enhancing transcriptional activity. The compound exhibits a favorable kinetic profile, promoting rapid receptor activation and subsequent downstream signaling. Additionally, its hydrophobic characteristics enable effective membrane penetration, influencing cellular localization and interaction dynamics. | ||||||
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
As an isomer of retinoic acid, it directly binds to RXRβ, potentially enhancing its expression through retinoid signaling pathways. | ||||||
Bexarotene d4 | 2182068-00-2 | sc-353071 | 10 mg | $4000.00 | ||
Bexarotene d4 functions as a selective RXR beta modulator, distinguished by its unique ability to induce specific conformational shifts in the receptor. This compound engages in intricate molecular interactions, promoting the formation of unique complexes with other nuclear receptors. Its distinct physicochemical properties enhance solubility and permeability, facilitating efficient cellular uptake. The compound's reaction kinetics reveal a rapid onset of action, influencing various signaling pathways and gene regulatory mechanisms. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C, which can lead to a cascade of signaling events influencing the expression of various proteins including RXRβ. | ||||||
Lithocholic acid | 434-13-9 | sc-215262 sc-215262A | 10 g 25 g | $100.00 $272.00 | 1 | |
A bile acid that may interact with nuclear receptors and modulate gene expression, possibly influencing RXRβ levels. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
A thiazolidinedione that acts as a PPARγ agonist, potentially altering the expression of genes regulated by PPARγ-RXRβ heterodimers. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Similar to pioglitazone, this compound is a PPARγ agonist and may affect RXRβ expression through PPARγ-RXRβ interaction. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $41.00 | 9 | |
As a PPARα agonist, fenofibrate could potentially influence RXRβ expression through PPARα-RXRβ heterodimer activity. | ||||||