Rsk Substrates
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
p70 S6 Rsk substrate | sc-3009 | 0.5 mg/0.1 ml | $96.00 | 18 | ||
p70 S6 Rsk substrate is a key player in the signaling cascade involving the RSK family of kinases, particularly in the phosphorylation of ribosomal protein S6. This substrate exhibits specific affinity for RSK, facilitating the transfer of phosphate groups that modulate protein synthesis and cell growth. Its interactions are crucial for the activation of downstream targets, influencing cellular responses to growth factors and stress, thereby playing a vital role in translational control and metabolic regulation. | ||||||
caspase-9 (Ser 196) | sc-24528 | 0.5 mg/0.1 ml | $96.00 | |||
Caspase-9 (Ser 196) functions as a critical regulator in apoptotic pathways, specifically through its role in the activation of downstream effector caspases. This enzyme exhibits unique substrate specificity, recognizing and cleaving target proteins at aspartate residues. Its activation is tightly controlled by apoptotic signals, leading to a cascade of proteolytic events that ultimately drive programmed cell death. The kinetics of caspase-9 activation are influenced by various apoptotic stimuli, highlighting its role in cellular homeostasis and response to stress. | ||||||
Nur77 (Ser 351) | sc-24530 | 0.5 mg/0.1 ml | $96.00 | |||
Nur77 (Ser 351) is a pivotal player in cellular signaling, particularly in the regulation of gene expression and apoptosis. This protein undergoes phosphorylation at Ser 351, which enhances its transcriptional activity and promotes interactions with specific nuclear receptors. Its unique ability to modulate distinct signaling pathways allows it to influence cellular responses to stress and inflammation. The kinetics of Nur77's activation are finely tuned, reflecting its role in maintaining cellular equilibrium. | ||||||
Adducin (Ser 662) | sc-24527 | 0.5 mg/0.1 ml | $96.00 | |||
Adducin (Ser 662) is a crucial cytoskeletal protein that plays a significant role in the assembly and stabilization of spectrin-actin networks. Phosphorylation at Ser 662 enhances its affinity for actin filaments, facilitating cytoskeletal remodeling. This modification influences cell shape and motility by modulating interactions with other cytoskeletal components. The kinetics of Adducin's assembly and disassembly are tightly regulated, impacting cellular dynamics and mechanical properties. | ||||||
Na+/K+-ATPase α (Ser 943) | sc-24529 | 0.5 mg/0.1 ml | $96.00 | |||
Na+/K+-ATPase α (Ser 943) is a pivotal enzyme in maintaining cellular ion homeostasis, specifically regulating sodium and potassium gradients across the plasma membrane. Phosphorylation at Ser 943 modulates its enzymatic activity, influencing ATP hydrolysis rates and ion transport efficiency. This modification alters the enzyme's conformational states, enhancing its interaction with specific substrates and affecting downstream signaling pathways. The enzyme's kinetic properties are finely tuned, ensuring optimal cellular function. | ||||||