RSBN1L Inhibitors
RSBN1L inhibitors are a class of chemical compounds that specifically target and inhibit the activity of the enzyme RSBN1L. RSBN1L, which is short for Round Spermatid Basic Protein 1-Like, is a protein that plays a fundamental role in various biological processes within cells. The inhibition of RSBN1L by these compounds can lead to alterations in the functioning of the cellular machinery that relies on this enzyme. The design of RSBN1L inhibitors often involves the identification of specific molecular structures that can bind to the active site of the RSBN1L enzyme or to other critical regions essential for its activity, thus preventing the enzyme from performing its normal function in the cell.
The study and development of RSBN1L inhibitors have been driven by the need to understand the intricate details of cellular processes and to explore the molecular underpinnings of various biological mechanisms. By inhibiting RSBN1L, researchers can observe changes in the biochemical pathways where RSBN1L is involved, leading to insights into the enzyme's role and the broader consequences of its inactivity. The specificity of RSBN1L inhibitors is paramount, as off-target effects can lead to unintended consequences within the cell. To achieve a high degree of specificity, RSBN1L inhibitors are designed using sophisticated techniques, including molecular modeling and structure-activity relationship studies, which help in refining the inhibitor's ability to bind selectively to RSBN1L. The creation and refinement of RSBN1L inhibitors continue to be a subject of interest in the field of biochemistry and molecular biology, contributing to the fundamental understanding of cellular function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules and consequently inhibits their disassembly, leading to cell cycle arrest. RSBN1L has been implicated in cellular processes involving microtubule dynamics; thus, paclitaxel's action could indirectly inhibit RSBN1L by disrupting its associated cellular processes. | ||||||
Mitoxantrone | 65271-80-9 | sc-207888 | 100 mg | $279.00 | 8 | |
Mitoxantrone intercalates into DNA and inhibits topoisomerase II, disrupting DNA replication and repair. RSBN1L, if involved in these pathways, would be indirectly inhibited due to the downstream effects on cellular proliferation and division. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin binds to FKBP12 and inhibits the mTOR pathway, which is crucial for cell growth and proliferation. Since RSBN1L is suggested to be involved in cell growth, inhibiting mTOR could indirectly diminish RSBN1L's functional activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent PI3K inhibitor which disrupts the PI3K/AKT pathway, potentially affecting processes that RSBN1L might be involved in, such as cell survival and metabolism, thus indirectly inhibiting its function. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib inhibits the 26S proteasome, preventing protein degradation. If RSBN1L is regulated via proteasomal degradation, bortezomib could indirectly increase RSBN1L levels, leading to a negative feedback loop that reduces its functional activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor which leads to changes in gene expression. If RSBN1L gene expression is controlled by acetylation status, this could indirectly affect RSBN1L's activity by altering its expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor, similar to wortmannin, and it can indirectly influence RSBN1L function by disrupting the PI3K/AKT pathway, which might be involved in the regulation of RSBN1L. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
Cyclosporin A inhibits calcineurin, thereby inhibiting T-cell activation. If RSBN1L plays a role in T-cell function, its activity could be indirectly inhibited by the action of cyclosporin A on the immune response. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $98.00 $315.00 $2244.00 $4396.00 $17850.00 $34068.00 | 3 | |
Colchicine binds to tubulin, preventing microtubule polymerization. If RSBN1L interacts with microtubules or is involved in cellular processes that depend on microtubule dynamics, colchicine could indirectly inhibit RSBN1L's function. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $100.00 $230.00 $450.00 $1715.00 $2900.00 | 4 | |
Vinblastine binds to tubulin and inhibits microtubule formation. By disrupting microtubule dynamics, it could indirectly impact RSBN1L activity if RSBN1L is involved in cellular processes that require intact microtubules. | ||||||