Date published: 2025-9-12

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Romo1 Activators

The class of ROMO1 Modulators comprises compounds that can influence the ROS production or the signaling pathways associated with ROMO1. H2O2, Rotenone, Antimycin A, Paraquat, Doxorubicin, Arsenic trioxide, Zinc, Copper, Iron, Sodium Arsenite, Cadmium, and Tert-butyl hydroperoxide are all compounds known to induce ROS production, which can potentially influence ROMO1. H2O2 is a strong oxidizer that can increase ROS production. Rotenone is a known inhibitor of mitochondrial complex I and can increase ROS production. Antimycin A, an antibiotic and an inhibitor of mitochondrial complex III, can also increase ROS production.

Paraquat, a herbicide, and Doxorubicin, an anthracycline antibiotic, can both induce ROS production. Arsenic trioxide can increase ROS production. Zinc, Copper, Iron, Sodium Arsenite, and Cadmium are all metals that can induce ROS production. Zinc, Copper, and Iron can induce ROS production through Fenton chemistry. Sodium Arsenite, a form of arsenic, can also induce ROS production. Cadmium, a heavy metal, can induce ROS production. Finally, Tert-butyl hydroperoxide, an organic peroxide, can increase ROS production, potentially influencing ROMO1. In conclusion, the "ROMO1 Modulators" comprises compounds that are not direct activators of ROMO1 but can indirectly influence its activity by affecting ROS production or related signaling pathways.

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