Date published: 2026-3-7

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RNase L Antibodies

Santa Cruz Biotechnology provides a broad selection of RNase L monoclonal antibodies for the detection and analysis of RNase L, a crucial enzyme involved in the antiviral response and regulation of cellular RNA levels. RNase L monoclonal antibodies are compatible with multiple research techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). RNase L plays a significant role in the innate immune response by degrading viral RNA, thereby limiting viral replication and spread. RNase L is involved in the regulation of apoptosis and cellular stress responses, making it a key focus in cancer research and therapeutic development. Understanding the function and regulation of RNase L is essential for elucidating its role in various diseases, including viral infections and cancer. RNase L research continues to reveal new insights into cellular defense mechanisms and potential therapeutic targets. Ongoing studies of RNase L expression patterns help identify biomarkers for disease progression and treatment response. RNase L investigation advances our understanding of RNA metabolism and cellular homeostasis. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific knowledge of RNase L and its impact on human health.

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RNase L Antibodies

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RNase L Antibody (E-9)

sc-74405mouse IgG2b κ442-741 (h)WB, IP, IF, IHC(P), ELISAm, r, h
10
(5)

RNase L Antibody (2E9.2G5)

sc-23955mouse IgG1 κFL (h)WB, IP, IF, IHC(P)h
2
(2)

RNase L Antibody (H-4)

sc-74416mouse IgG2a κ442-741 (h)WB, IP, IF, IHC(P), ELISAh

new

(2)

RNase L CRISPR Knockout, HDR and Double Nickase Plasmids

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RNase L CRISPR/Cas9 KO Plasmid (h)

sc-403412hGene KnockoutGFP0
(0)

RNase L HDR Plasmid (h)

sc-403412-HDRhHomology Directed RepairPuromycin0
(0)

RNase L Double Nickase Plasmid (h)

sc-403412-NIChGene KnockoutPuromycin0
(0)

RNase L Double Nickase Plasmid (h2)

sc-403412-NIC-2hGene KnockoutPuromycin0
(0)

RNase L CRISPR/Cas9 KO Plasmid (m)

sc-423948mGene KnockoutGFP0
(0)

RNase L HDR Plasmid (m)

sc-423948-HDRmHomology Directed RepairPuromycin0
(0)

RNase L CRISPR Activation Products

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RNase L CRISPR Activation Plasmid (h)

sc-403412-ACThGene ActivationPuro, Blast, Hygro0
(0)

RNase L siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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RNase L siRNA (h)

sc-45965hGene SilencingN/A
8
(0)

RNase L shRNA Plasmid (h)

sc-45965-SHhGene SilencingPuromycin
8
(0)

RNase L shRNA (h) Lentiviral Particles

sc-45965-VhGene SilencingPuromycin
8
(0)

RNase L siRNA (m)

sc-45966mGene SilencingN/A
1
(1)

RNase L shRNA Plasmid (m)

sc-45966-SHmGene SilencingPuromycin
1
(1)

RNase L shRNA (m) Lentiviral Particles

sc-45966-VmGene SilencingPuromycin
1
(1)