RGD1304773 Inhibitors
RGD1304773 inhibitors represent a class of compounds designed to specifically target and modulate the activity of enzymes or proteins involved in cellular signaling pathways, often associated with the regulation of protein-protein interactions. These inhibitors are characterized by their high specificity and affinity for binding sites, often at the interface of critical proteins that participate in complex signaling mechanisms. Structurally, RGD1304773 inhibitors are engineered to mimic certain binding motifs found in natural substrates, allowing them to competitively inhibit or alter the interactions between proteins and enzymes. The RGD1304773 designation typically refers to the core scaffold or molecular structure that these inhibitors share, though variations in functional groups can lead to different binding affinities or specificities across different targets. This class of inhibitors is often designed with considerations for molecular stability, bioavailability, and the ability to effectively penetrate cellular membranes, which are important factors in optimizing their chemical properties.
From a chemical perspective, RGD1304773 inhibitors are usually composed of a central scaffold that is modified with various side chains, often containing hydrophobic and hydrophilic moieties to fine-tune their solubility and interaction with target proteins. The modifications on the central structure allow for increased flexibility in targeting specific protein-protein interfaces, making these inhibitors highly adaptable for various biochemical contexts. Researchers interested in the molecular dynamics of these compounds often focus on their binding kinetics, such as association and dissociation rates, which provide insights into their efficacy in modulating biological processes at a molecular level. Additionally, structural studies, including X-ray crystallography and molecular docking simulations, are essential in understanding the precise interactions between RGD1304773 inhibitors and their protein targets, helping to design more effective variants that enhance their binding specificity and stability.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin may inhibit the expression of COP1, E3 ubiquitin ligase by interfering with the activation of specific transcription factors and signaling pathways involved in the upregulation of COP1. It has been shown to modulate the activity of certain regulatory proteins, thus leading to the downregulation of COP1 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol has the potential to inhibit the expression of COP1, E3 ubiquitin ligase by modulating the activity of key regulatory genes and transcription factors. It can interfere with specific signaling pathways that are involved in the upregulation of COP1, thus exerting a suppressive effect on its expression, which is crucial for protein degradation and cellular regulation processes. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein may inhibit the expression of COP1, E3 ubiquitin ligase through its action on specific receptors and its interference with the signaling pathways responsible for the upregulation of this protein. It has the potential to modulate the activity of certain regulatory proteins and transcription factors involved in the regulation of COP1, thereby leading to its downregulation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is capable of inhibiting the expression of COP1, E3 ubiquitin ligase by interfering with the activity of certain kinases and transcription factors involved in the regulation of this protein. It can modulate the expression of key regulatory genes and interfere with specific signaling pathways that are crucial for the upregulation of COP1, leading to its downregulation and subsequent impact on protein stability. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine may inhibit the expression of COP1, E3 ubiquitin ligase by modulating the expression of key regulatory genes and interfering with specific signaling pathways that are involved in the upregulation of this protein. It has the potential to interfere with the activity of certain kinases and transcription factors crucial for the regulation of COP1, thus leading to its downregulation and subsequent impact on protein stability. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate has the potential to inhibit the expression of COP1, E3 ubiquitin ligase through its ability to modulate the activity of certain transcription factors and to interfere with the signaling pathways responsible for the upregulation of this protein. It can exert a suppressive effect on the expression of COP1, which is crucial for protein degradation and cellular regulation processes. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin may inhibit the expression of COP1, E3 ubiquitin ligase by interfering with the activity of specific kinases and transcription factors involved in the regulation of this protein. It can modulate the activity of certain regulatory proteins and interfere with specific signaling pathways that are crucial for the upregulation of COP1, leading to its downregulation and subsequent impact on protein stability. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $51.00 $77.00 $102.00 $153.00 $2856.00 | 7 | |
Fisetin has been shown to inhibit the expression of COP1, E3 ubiquitin ligase by modulating the activity of certain signaling pathways and by interfering with the function of specific regulatory proteins involved in the upregulation of this protein. It can interfere with the activation of specific transcription factors and signaling pathways crucial for the upregulation of COP1, leading to its downregulation and subsequent impact on protein stability. | ||||||
Baicalein | 491-67-8 | sc-200494 sc-200494A sc-200494B sc-200494C | 10 mg 100 mg 500 mg 1 g | $31.00 $41.00 $159.00 $286.00 | 12 | |
Baicalein is capable of inhibiting the expression of COP1, E3 ubiquitin ligase by modulating the activity of certain kinases and transcription factors involved in the regulation of this protein. It has the potential to interfere with the expression of key regulatory genes and specific signaling pathways that are crucial for the upregulation of COP1, leading to its downregulation and subsequent impact on protein stability. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $54.00 $112.00 $202.00 $700.00 | 6 | |
Silibinin may inhibit the expression of COP1, E3 ubiquitin ligase by modulating the expression of key regulatory genes and interfering with specific signaling pathways that are involved in the upregulation of this protein. It has the potential to interfere with the activity of certain kinases and transcription factors crucial for the regulation of COP1, thus leading to its downregulation and subsequent impact on protein stability. | ||||||