Date published: 2025-10-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

RFXDC2 Inhibitors

The term RFXDC2 inhibitors refers to a class of compounds that would interact with the RFXDC2 protein, where RFXDC2 stands for Regulatory Factor X Domain Containing 2. As the name suggests, this protein is part of the regulatory factor X (RFX) family, which includes transcription factors known to bind DNA and regulate the expression of various genes. However, the specific functions of RFXDC2, as well as the pathways and processes it may be involved in, would need to be deeply understood before a targeted class of inhibitors could be developed. The concept of RFXDC2 inhibitors presupposes that the protein has a well-defined role and that modulation of its activity through small molecule inhibitors is of interest for research.

If scientists were to pursue the development of RFXDC2 inhibitors, the initial phase would involve an extensive investigation into the protein's structure and the identification of potential binding sites for inhibitors. This could include regions that are critical for the protein's ability to bind DNA or interact with other proteins. Advanced structural analysis techniques, such as X-ray crystallography or cryo-electron microscopy, could be employed to determine the three-dimensional structure of RFXDC2. With this structural information, researchers would have a blueprint for understanding how the protein functions at the molecular level and where potential inhibitors could exert their effects. This structural knowledge is particularly important for the rational design of small molecules that can specifically bind to and inhibit RFXDC2 without affecting other members of the RFX family or unrelated proteins.

SEE ALSO...

Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$88.00
$200.00
13
(1)

Triptolide is known to inhibit the transcription of various genes by affecting RNA polymerase II activity. This broad action could potentially reduce the expression of a wide range of proteins, including transcription factors.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Actinomycin D intercalates into DNA and prevents the transcription of mRNA. It is a potent transcription inhibitor that could nonspecifically reduce RFXDC2 expression.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

DRB inhibits RNA polymerase II and could reduce the expression of proteins by inhibiting mRNA synthesis.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Mithramycin A binds to GC-rich DNA sequences and blocks transcription factor access to these sites, which could downregulate expression of certain genes.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

α-Amanitin is a potent inhibitor of RNA polymerase II and could lead to a general decrease in gene transcription, potentially affecting RFXDC2 expression.

Chidamide

743420-02-2sc-364462
sc-364462A
sc-364462B
1 mg
5 mg
25 mg
$61.00
$245.00
$1173.00
(1)

Chetomin disrupts the structure of the transcription factor complex, potentially reducing the transcription of genes regulated by those factors.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$226.00
$846.00
1
(0)

JQ1 is a BET bromodomain inhibitor that displaces bromodomain-containing proteins from chromatin, potentially leading to downregulation of some genes.

Olaparib

763113-22-0sc-302017
sc-302017A
sc-302017B
250 mg
500 mg
1 g
$206.00
$299.00
$485.00
10
(1)

Olaparib is a PARP inhibitor that could influence gene expression profiles by affecting DNA damage response pathways.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

SAHA is a histone deacetylase inhibitor that can lead to a global change in gene expression by altering chromatin structure.

Pladienolide B

445493-23-2sc-391691
sc-391691B
sc-391691A
sc-391691C
sc-391691D
sc-391691E
0.5 mg
10 mg
20 mg
50 mg
100 mg
5 mg
$290.00
$5572.00
$10815.00
$25000.00
$65000.00
$2781.00
63
(2)

Pladienolide B binds to the spliceosome and can disrupt splicing, potentially leading to altered mRNA processing and reduced protein expression.