Date published: 2026-4-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

RFC5 Inhibitors

RFC5 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the Replication Factor C5 (RFC5) protein. RFC5 is a critical component of the eukaryotic cell's DNA replication machinery, playing a pivotal role in ensuring the accurate duplication of genetic material during cell division. Inhibitors of RFC5 are primarily designed for research purposes to investigate the fundamental biological processes associated with DNA replication and cellular proliferation. These compounds are valuable tools for molecular biologists and cell biologists studying DNA replication mechanisms, as they allow researchers to manipulate and study the precise functions of RFC5 within the cell.

RFC5 inhibitors are typically small molecules that interact with the RFC5 protein, disrupting its normal function. By inhibiting RFC5, these compounds can lead to the impairment of DNA replication, which can, in turn, provide insights into the consequences of such disruptions on cell growth, genomic stability, and other cellular processes. Researchers use RFC5 inhibitors in laboratory settings to probe the intricate details of DNA replication, exploring its regulation, potential vulnerabilities, and the consequences of its dysregulation. These inhibitors can serve as invaluable research tools for elucidating the molecular intricacies of DNA replication and furthering our understanding of the fundamental processes that govern cell division and genetic inheritance. While RFC5 inhibitors may have potential applications beyond basic research, their primary purpose is to aid scientists in deciphering the complexities of DNA replication at the molecular level.

SEE ALSO...

Items 1 to 10 of 12 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

A cytidine analog that incorporates into DNA and RNA, potentially disrupting DNA methylation and gene expression, possibly affecting RFC5 levels.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

An inhibitor of histone deacetylase that could alter chromatin structure and indirectly impact RFC5 transcription.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$133.00
$275.00
37
(2)

A histone deacetylase inhibitor that may change gene expression patterns, possibly influencing RFC5 expression.

MG-132 [Z-Leu- Leu-Leu-CHO]

133407-82-6sc-201270
sc-201270A
sc-201270B
5 mg
25 mg
100 mg
$60.00
$265.00
$1000.00
163
(3)

A proteasome inhibitor that could stabilize proteins that regulate RFC5 expression through proteasomal degradation pathways.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor that might affect signaling pathways, potentially altering the transcription of various genes including RFC5.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

An mTOR inhibitor that could impact cellular growth pathways, thereby possibly affecting RFC5 expression indirectly.

Nutlin-3

548472-68-0sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
$62.00
$225.00
$779.00
24
(1)

A small molecule that disrupts the interaction between p53 and MDM2, potentially changing the expression of p53-regulated genes, possibly including RFC5.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

A proteasome inhibitor that may affect the turnover of proteins involved in the regulation of RFC5 gene expression.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

A short-chain fatty acid that acts as a histone deacetylase inhibitor, potentially influencing RFC5 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

A metabolite of vitamin A that modulates gene expression, which could have an indirect effect on RFC5 expression levels.