Date published: 2026-5-30

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RASSF3 Inhibitors

RASSF3 inhibitors represent a distinctive category of chemical compounds specifically designed to target and modulate the activity of RASSF3, which stands for Ras Association Domain Family Member 3. RASSF3 is a crucial protein within the RASSF family, known for its involvement in various intracellular signaling pathways. This family is characterized by the presence of Ras-association (RA) domains that interact with small GTPases, such as Ras and Rap, thereby influencing downstream signaling cascades. RASSF3, in particular, has been implicated in cell cycle regulation, apoptosis, and tumor suppression, among other cellular processes. Inhibitors directed at RASSF3 are developed to interact with this specific protein, potentially influencing its interactions with other signaling molecules and affecting the cellular pathways in which RASSF3 is involved.

Structurally, RASSF3 inhibitors are designed to interact with particular regions or binding sites on the RASSF3 protein, thereby potentially disrupting its interactions with regulatory partners. These inhibitors can impact RASSF3-mediated signaling events and the downstream cellular responses associated with them. While the precise mechanisms by which RASSF3 inhibitors exert their effects can vary, their primary objective is to provide researchers with valuable tools for exploring the roles and functions of RASSF3 in cellular processes. Investigating the biochemical and structural aspects of RASSF3, as well as its modulation by inhibitors, can contribute to a deeper understanding of intracellular signaling networks and their implications for cell biology and potentially inform future research directions in the field of molecular and cellular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Farnesyl thiosalicylic acid

162520-00-5sc-205322
sc-205322A
1 mg
5 mg
$61.00
$82.00
15
(1)

Tipifarnib inhibits the post-translational modification of Ras, potentially influencing RASSF3 function in the Ras pathway.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Sorafenib targets multiple kinases, including some in the Ras pathway, possibly affecting RASSF3 indirectly.

Selumetinib

606143-52-6sc-364613
sc-364613A
sc-364613B
sc-364613C
sc-364613D
5 mg
10 mg
100 mg
500 mg
1 g
$29.00
$82.00
$420.00
$1897.00
$3021.00
5
(1)

As a MEK inhibitor, Selumetinib acts downstream of Ras and may influence RASSF3's role in the pathway.

Trametinib

871700-17-3sc-364639
sc-364639A
sc-364639B
5 mg
10 mg
1 g
$114.00
$166.00
$947.00
19
(1)

Trametinib is another MEK inhibitor that might have indirect effects on RASSF3 due to its role in the Ras pathway.

Cobimetinib

934660-93-2sc-507421
5 mg
$270.00
(0)

Cobimetinib, a MEK inhibitor, might indirectly influence RASSF3's role in the Ras pathway.

BAY 869766

923032-37-5sc-364427
sc-364427A
5 mg
10 mg
$245.00
$428.00
1
(1)

This compound is a MEK inhibitor that may influence RASSF3's function indirectly.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

By inhibiting JNK, SP600125 may indirectly affect Ras signaling and RASSF3's role in it.

Manumycin A

52665-74-4sc-200857
sc-200857A
1 mg
5 mg
$219.00
$634.00
5
(1)

As a farnesyltransferase inhibitor, it might influence Ras post-translational modification and indirectly RASSF3.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

By inhibiting PI3K, a downstream effector of Ras, LY294002 might indirectly affect RASSF3 function.