Rab 39B Activators
Rab 39B activators encompass a range of chemicals that primarily target intracellular trafficking pathways, thereby influencing the function or activity of Rab 39B. The RAB protein family, including Rab 39B, plays pivotal roles in vesicle formation, transportation, and fusion. Several of the mentioned activators, such as GTP-γ-S, can lock RAB proteins in their active state by mimicking GTP's effects, which RAB proteins utilize for their function.
In addition to direct modulators, other chemicals like Brefeldin A and Nocodazole indirectly impact the RAB protein functionality by altering the cellular structures or processes they interact with. For instance, Brefeldin A disrupts the Golgi apparatus, an organelle where many RAB proteins operate, affecting vesicle trafficking dynamics. Meanwhile, compounds like Wortmannin and LY294002, which modulate specific kinase pathways, can also modify the landscape of intracellular trafficking, given the integral role of phosphorylation in these processes.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Guanosine 5′-O-(3-thiotriphosphate) tetralithium salt | 94825-44-2 | sc-202639 | 10 mg | $465.00 | ||
A non-hydrolyzable GTP analog, can lock RAB proteins in an active state, potentially influencing Rab 39B activity. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
This compound disrupts the Golgi apparatus, indirectly modulating RAB protein-mediated trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
By disrupting microtubules, nocodazole can affect vesicle transport processes involving RAB proteins. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
An inhibitor of phosphoinositide 3-kinases, wortmannin might affect intracellular trafficking mediated by RAB proteins. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Influences intracellular trafficking by disrupting the Golgi and endosomal pH, potentially affecting RAB protein function. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Affects clathrin-mediated endocytosis, potentially influencing RAB protein-mediated pathways. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
As a dynamin inhibitor, dynasore can affect endocytosis processes in which RAB proteins might be involved. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
This aminoglycoside antibiotic can interfere with phospholipids and potentially influence RAB-mediated processes. | ||||||
Methyl-β-cyclodextrin | 128446-36-6 | sc-215379A sc-215379 sc-215379C sc-215379B | 100 mg 1 g 10 g 5 g | $20.00 $48.00 $160.00 $82.00 | 19 | |
Affects cholesterol-rich domains in membranes, which can indirectly impact RAB protein-mediated trafficking. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Elevates intracellular cAMP, potentially influencing intracellular trafficking processes mediated by RAB proteins. | ||||||