Date published: 2025-9-18

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Quenchers

Santa Cruz Biotechnology now offers a broad range of quenchers for use in various applications. Quenchers are specialized chemical compounds that play a crucial role in fluorescence-based assays and other biochemical experiments by absorbing fluorescence emitted by reporter molecules. This category of chemicals is essential in scientific research, particularly in the fields of molecular biology, genomics, and proteomics, where precise measurement and control of fluorescence signals are necessary. Quenchers are used to reduce background fluorescence, thereby enhancing the accuracy and sensitivity of quantitative assays, such as real-time PCR, FRET (Frster Resonance Energy Transfer) assays, and DNA sequencing. These compounds enable researchers to monitor biochemical processes in real-time, offering invaluable insights into molecular interactions and dynamic changes within cells. The ability to modulate fluorescence signals with quenchers has made them indispensable tools in the study of gene expression, protein-protein interactions, and the elucidation of complex biological pathways. As a result, quenchers are a fundamental component in advancing scientific knowledge and technological innovations in various research domains. View detailed information on our available quenchers by clicking on the product name.

Items 31 to 40 of 62 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

CruzQuench™ 4 amine

sc-362650
1 mg
$195.00
(0)

CruzQuench™ 4 amine stands out as a versatile quencher due to its unique ability to form strong hydrogen bonds, which significantly influences its interaction with excited-state species. This compound exhibits a remarkable affinity for electron-rich environments, enhancing its quenching capabilities. Its distinct molecular architecture allows for efficient energy dissipation pathways, leading to rapid deactivation of excited states and fine-tuning of photophysical properties across various conditions.

CruzQuench™ 4 azide

sc-362651
1 mg
$195.00
(0)

CruzQuench™ 4 azide is distinguished by its unique ability to engage in specific π-π stacking interactions, which enhances its quenching efficiency. This compound demonstrates a rapid reaction kinetics profile, facilitating swift energy transfer processes. Its structural features promote effective non-radiative decay pathways, allowing for precise modulation of luminescent properties. The compound's stability under varying conditions further contributes to its reliable performance as a quencher.

CruzQuench™ 4 CPG 1000 Å

sc-362652
1 g
$950.00
(0)

CruzQuench™ 4 CPG 1000 Å exhibits remarkable selectivity in quenching mechanisms, primarily through its ability to form strong hydrogen bonds with excited-state molecules. This interaction leads to enhanced energy dissipation via vibrational relaxation pathways. The compound's unique structural arrangement allows for efficient electronic coupling, optimizing its quenching efficiency. Additionally, its robust thermal stability ensures consistent performance across diverse experimental conditions.

CruzQuench™ 4 CPG 500 Å

sc-362653
1 g
$1450.00
(0)

CruzQuench™ 4 CPG 500 Å stands out for its exceptional ability to modulate fluorescence through specific electron transfer processes. Its unique molecular architecture facilitates rapid energy transfer, effectively reducing excited-state lifetimes. The compound's high affinity for certain chromophores enhances quenching efficiency, while its tailored surface properties promote optimal interactions with target molecules. This results in a finely tuned quenching profile, adaptable to various experimental setups.

CruzQuench™ 4 succinimidyl ester

sc-362656
5 mg
$195.00
(0)

CruzQuench™ 4 succinimidyl ester exhibits remarkable quenching capabilities through its strategic molecular design, which allows for selective interactions with fluorophores. Its ester functionality enhances reactivity, enabling efficient conjugation with amine-containing compounds. The compound's unique steric properties facilitate precise spatial orientation, optimizing energy dissipation pathways. This results in a robust quenching mechanism, characterized by rapid kinetics and high specificity, making it suitable for diverse applications in fluorescence studies.

CruzQuench™ 5 alkyne

sc-362658
1 mg
$195.00
(0)

CruzQuench™ 5 alkyne serves as an effective quencher, distinguished by its unique alkyne structure that promotes specific π-π stacking interactions with excited-state fluorophores. This compound's linear geometry enhances its ability to engage in non-covalent interactions, leading to efficient energy transfer and quenching. Its rapid reaction kinetics and selective binding properties enable precise modulation of fluorescence signals, making it a powerful tool for studying dynamic molecular processes.

CruzQuench™ 5 amine

sc-362659
1 mg
$195.00
(0)

CruzQuench™ 5 amine is a specialized quencher characterized by its amine functional group, which facilitates strong hydrogen bonding interactions with excited-state species. This compound exhibits unique electron-donating properties, enhancing its ability to stabilize excited states and promote non-radiative decay pathways. Its versatile reactivity allows for tailored quenching efficiency, making it an essential component in fine-tuning fluorescence dynamics in various experimental settings.

CruzQuench™ 5 CPG 1000 Å

sc-362661
1 g
$1950.00
(0)

CruzQuench™ 5 CPG 1000 Å is a sophisticated quencher distinguished by its unique structural framework, which enables effective energy transfer through π-π stacking interactions. This compound exhibits a high degree of selectivity in quenching excited-state species, driven by its tailored steric and electronic properties. Its ability to modulate reaction kinetics enhances the precision of fluorescence measurements, making it a critical tool for optimizing photophysical studies.

CruzQuench™ 5 CPG 500 Å

sc-362662
1 g
$2462.00
(0)

CruzQuench™ 5 CPG 500 Å is an advanced quencher characterized by its unique molecular architecture that facilitates efficient energy dissipation via non-radiative pathways. Its specific interactions with excited-state molecules are influenced by tailored electronic environments, allowing for enhanced quenching efficiency. This compound's distinctive physical properties contribute to its ability to fine-tune reaction dynamics, making it essential for precise fluorescence applications and studies of molecular behavior.

CruzQuench™ 5 succinimidyl ester

sc-362665
5 mg
$195.00
(0)

CruzQuench™ 5 succinimidyl ester is a specialized quencher known for its robust reactivity and selective interaction with amine groups. Its unique ester functionality enables rapid conjugation, promoting efficient energy transfer and quenching through dynamic molecular interactions. The compound's structural design enhances its ability to modulate fluorescence intensity, providing a versatile tool for exploring complex biochemical pathways and optimizing reaction kinetics in various experimental setups.