PSM Activators
The chemical class of PSM activators comprises a diverse array of compounds that can influence the expression or activity of PSM through various cellular pathways. Forskolin, for instance, acts as an activator of adenylate cyclase, leading to increased intracellular cAMP levels. This elevation in cAMP can activate protein kinase A (PKA), which may modulate PSM through downstream signaling pathways, influencing cellular growth and differentiation. PMA (Phorbol 12-myristate) is a phorbol ester that activates protein kinase C (PKC), impacting various cellular processes. PKC-mediated pathways can influence PSM through the modulation of transcription factors and other signaling molecules. Dibutyryl cAMP, a cell-permeable analog of cAMP, directly elevates intracellular cAMP levels, activating PKA and influencing PSM expression or activity through downstream signaling cascades. A23187, a calcium ionophore, facilitates the influx of calcium into cells. Elevated intracellular calcium levels can activate calcium-dependent signaling pathways, modulating PSM through calcium-sensitive processes. 6-Benzylaminopurine, a synthetic cytokinin, influences cell division and differentiation, impacting PSM through cellular processes related to growth and differentiation.
Retinoic Acid, as a ligand for nuclear retinoic acid receptors (RARs), modulates gene expression and may influence PSM through retinoic acid-responsive elements in the genome. DHPG (Dihydroxyphenylglycine), a selective agonist for metabotropic glutamate receptors (mGluRs), can influence PSM through the modulation of intracellular signaling cascades. Bay K 8644, a dihydropyridine calcium channel activator, enhances calcium influx, leading to the activation of signaling pathways and transcription factors that may impact PSM. N6-Cyclopentyladenosine, a selective adenosine A1 receptor agonist, modulates intracellular signaling pathways and influences PSM through the downstream effects of adenosine receptor activation. Ionomycin, a calcium ionophore similar to A23187, facilitates calcium influx into cells, modulating PSM through calcium-sensitive processes. GW0742, a synthetic agonist for peroxisome proliferator-activated receptor delta (PPARδ), can influence PSM through the modulation of gene expression and related signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an activator of adenylate cyclase, leading to increased intracellular cAMP levels. This elevation in cAMP can activate protein kinase A (PKA), which may modulate PSM through downstream signaling pathways, including those involved in cellular growth and differentiation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA, a phorbol ester, activates protein kinase C (PKC), influencing various cellular processes. PKC-mediated pathways can impact PSM through modulation of transcription factors and other signaling molecules. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl cAMP is a cell-permeable analog of cAMP, directly elevating intracellular cAMP levels. Increased cAMP can activate PKA, potentially influencing PSM expression or activity through downstream signaling cascades. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 is a calcium ionophore that facilitates the influx of calcium into cells. Elevated intracellular calcium levels can activate calcium-dependent signaling pathways, potentially modulating PSM through calcium-sensitive processes. | ||||||
6-Benzylaminopurine | 1214-39-7 | sc-202428 sc-202428A | 1 g 5 g | $20.00 $52.00 | ||
6-Benzylaminopurine is a synthetic cytokinin that can influence cell division and differentiation. By affecting cytokinin pathways, this chemical may impact PSM through cellular processes related to growth and differentiation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid is a biologically active form of vitamin A that acts as a ligand for nuclear retinoic acid receptors (RARs). RAR activation can modulate gene expression, potentially influencing PSM through retinoic acid-responsive elements in the genome. | ||||||
(RS)-3,5-DHPG | 19641-83-9 | sc-205496 sc-205496A | 10 mg 50 mg | $152.00 $632.00 | ||
DHPG is a selective agonist for metabotropic glutamate receptors (mGluRs), particularly mGluR1 and mGluR5. Activation of mGluRs can influence various cellular processes, potentially impacting PSM through the modulation of intracellular signaling cascades. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $84.00 $196.00 $817.00 | ||
Bay K 8644 is a dihydropyridine calcium channel activator that enhances calcium influx. Increased calcium levels can activate signaling pathways and transcription factors, potentially influencing PSM through calcium-dependent processes. | ||||||
N6-Cyclopentyladenosine | 41552-82-3 | sc-204117 | 50 mg | $120.00 | 2 | |
N6-Cyclopentyladenosine is a selective adenosine A1 receptor agonist. Activation of A1 receptors can modulate intracellular signaling pathways, potentially influencing PSM through the downstream effects of adenosine receptor activation. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 (PGE2) is a lipid mediator that acts through G-protein-coupled receptors, including EP receptors. PGE2 signaling can activate various intracellular pathways, potentially impacting PSM through EP receptor-mediated signaling cascades. | ||||||