Date published: 2025-10-25

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PRAMEF18 Inhibitors

PRAMEF18 inhibitors constitute a distinct chemical class designed to modulate the activity of the PRAMEF18 protein. PRAMEF18, a member of the PRAME (preferentially expressed antigen in melanoma) family, is associated with various cellular processes, including gene regulation and modulation of immune responses. Inhibitors targeting PRAMEF18 operate by disrupting its normal functions within these pathways, thereby influencing the intricate molecular processes that involve this protein. PRAMEF18 inhibitors exert their effects by interfering with the molecular interactions and signaling cascades associated with PRAMEF18, potentially leading to altered gene expression patterns and modulation of immune responses.

The specific mechanism of action of PRAMEF18 inhibitors is centered around the disruption of molecular pathways where PRAMEF18 plays a crucial role. By perturbing these pathways, these inhibitors can potentially influence cellular processes regulated by PRAMEF18, providing researchers with valuable tools to explore the intricate molecular networks associated with gene expression and immune modulation. Understanding the role of PRAMEF18 and the impact of its inhibition contributes to the broader knowledge of cellular biology, offering insights into the intricate molecular processes involved in gene regulation and immune responses. PRAMEF18 inhibitors serve as crucial instruments in deciphering the molecular intricacies of these pathways and expanding our comprehension of the biological factors influencing cellular behavior.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine causes demethylation of DNA, potentially reversing epigenetic silencing and affecting gene expression, including possibly reducing PRAMEF18 expression.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Decitabine is a DNA methyltransferase inhibitor, leading to DNA demethylation and potentially altering the expression of various genes including PRAMEF18.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A inhibits histone deacetylase, causing changes in chromatin structure and potentially downregulating genes like PRAMEF18.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat, another histone deacetylase inhibitor, could affect gene expression patterns, potentially including PRAMEF18.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

Entinostat, a class I histone deacetylase inhibitor, may change the expression of certain genes, which could include PRAMEF18.

Romidepsin

128517-07-7sc-364603
sc-364603A
1 mg
5 mg
$214.00
$622.00
1
(1)

Romidepsin is a histone deacetylase inhibitor that can modify the expression of various genes, potentially including PRAMEF18.

RG 108

48208-26-0sc-204235
sc-204235A
10 mg
50 mg
$128.00
$505.00
2
(1)

RG108 is a DNA methyltransferase inhibitor that does not incorporate into DNA but can still potentially influence gene expression, including PRAMEF18.

Mithramycin A

18378-89-7sc-200909
1 mg
$54.00
6
(1)

Mithramycin A binds to DNA and inhibits RNA polymerase, which could reduce the expression of PRAMEF18.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

Disulfiram can modulate NF-kB activity and may have off-target effects that alter gene expression, including potential reduction of PRAMEF18 expression.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$79.00
$300.00
32
(2)

Parthenolide can inhibit NF-kB signaling, which might result in the decreased expression of certain genes, possibly including PRAMEF18.