PRAMEF16 Activators
The chemical class known as PRAMEF16 Activators encompasses a group of compounds that can influence the expression and activity of the PRAMEF16 protein. These activators are primarily involved in the modulation of epigenetic mechanisms and cellular signaling pathways. Epigenetic modulators within this class, such as DNA methyltransferase inhibitors and histone deacetylase inhibitors, can alter the chromatin structure, facilitating a more transcriptionally active state. By changing the epigenetic marks on DNA and histones, these chemicals can encourage the transcription machinery to access specific genes, which can lead to increased gene expression.
Moreover, members of the PRAMEF16 Activators class can affect intracellular signaling cascades, which are integral to a wide array of cellular processes including gene expression. Certain compounds in this class can inhibit kinases, thereby altering phosphorylation patterns that serve as on/off switches for many proteins and enzymes within the cell. This can result in the activation or repression of various genes. Additionally, some activators work by modulating the activity of transcription factors such as NF-kB, which, upon inhibition, can change the expression profile of a cell, potentially leading to an increase in expression of proteins like PRAMEF16. These activators thus play a role in the intricate network of cellular communication and gene regulation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Acts on gene expression through retinoid receptors, which could influence the transcriptional activity of genes, potentially including PRAMEF16. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
Modifies the activity of various enzymes and could lead to epigenetic changes that result in gene activation, possibly affecting PRAMEF16 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a tyrosine kinase inhibitor, it can modulate signaling pathways and could activate certain genes, potentially including PRAMEF16. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
Inhibits DNA methyltransferases, possibly causing demethylation and activation of genes, which may affect PRAMEF16. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $196.00 | 9 | |
A potent histone deacetylase inhibitor that could lead to alterations in gene expression and potentially affect PRAMEF16. | ||||||
6-Thioguanine | 154-42-7 | sc-205587 sc-205587A | 250 mg 500 mg | $41.00 $53.00 | 3 | |
May act as a histone deacetylase inhibitor and could potentially activate gene expression, including that of PRAMEF16. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
By inhibiting NF-kB, it could lead to changes in the expression of genes regulated by this factor, which might affect PRAMEF16. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Another histone deacetylase inhibitor that could lead to increased expression of a range of genes, potentially PRAMEF16. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Affects gene expression via its impact on histone deacetylase and could potentially influence the expression of PRAMEF16. | ||||||