| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
α-Amanitin is a potent inhibitor of RNA polymerase II and III, specifically disrupting transcription processes in eukaryotic cells. Its unique cyclic peptide structure allows for strong binding to the enzyme's active site, preventing RNA synthesis. The compound's selective affinity for these polymerases leads to distinct kinetic profiles, significantly altering gene expression. Its stability in cellular environments enhances its effectiveness in modulating transcriptional activity, making it a critical tool in studying RNA dynamics. | ||||||
Juglone | 481-39-0 | sc-202675 sc-202675A | 1 g 5 g | $67.00 $226.00 | 6 | |
Juglone is a naturally occurring naphthoquinone that exhibits unique interactions with various biological systems. As a potent inhibitor of RNA polymerase III, it disrupts the transcription of small RNAs, influencing gene regulation. Its ability to form stable complexes with metal ions enhances its reactivity, while its redox properties facilitate electron transfer processes. Juglone's distinct molecular structure allows for selective binding, impacting cellular pathways and metabolic functions. | ||||||