PKC beta Activators
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
1-Stearoyl-2-arachidonoyl-sn-glycerol | 65914-84-3 | sc-202864 | 10 mg | $175.00 | ||
1-Stearoyl-2-arachidonoyl-sn-glycerol serves as a potent activator of PKC beta, influencing various signaling pathways. Its unique fatty acid composition allows for specific membrane interactions, enhancing its affinity for lipid rafts. This localization promotes the phosphorylation of target proteins, modulating cellular responses. The distinct acyl chain structure contributes to its role in regulating cellular growth and differentiation, showcasing its importance in signal transduction mechanisms. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a direct activator of PKC β. It binds to the C1 domain of PKC β, mimicking diacylglycerol (DAG), a natural activator of PKC. This binding leads to conformational changes in PKC β, enabling its activation and subsequent phosphorylation of downstream substrates involved in cellular signaling pathways. | ||||||
Bryostatin 1 | 83314-01-6 | sc-201407 | 10 µg | $240.00 | 9 | |
Bryostatin 1 is another direct activator of PKC β. It interacts with the C1 domain of PKC β, promoting its activation. This compound has been explored for its potential therapeutic applications in various medical research contexts. | ||||||
Prostratin | 60857-08-1 | sc-203422 sc-203422A | 1 mg 5 mg | $138.00 $530.00 | 24 | |
Prostratin is known to activate PKC β by binding to the C1 domain. It triggers the activation of PKC β and influences downstream signaling pathways associated with cellular responses. | ||||||
Ingenol 3-angelate | 75567-37-2 | sc-364214 sc-364214A | 1 mg 5 mg | $189.00 $734.00 | 3 | |
Like PMA and TPA, Ingenol 3-angelate is a direct activator of PKC β. It binds to the C1 domain, facilitating PKC β activation and its subsequent roles in various cellular processes. | ||||||
Diosgenin | 512-04-9 | sc-205652 sc-205652B sc-205652A | 5 g 25 g 100 g | $46.00 $128.00 $507.00 | 4 | |
While not a direct activator, Diosgenin may influence PKC β activity through indirect mechanisms, potentially by modulating signaling pathways or cellular processes that impact PKC β. | ||||||
Chelerythrine | 34316-15-9 | sc-507380 | 100 mg | $540.00 | ||
Chelerythrine inhibits PKC β by binding to its kinase domain, thereby preventing its activation and the subsequent phosphorylation of target proteins. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Similarly, Betulinic acid inhibits PKC β by binding to its kinase domain, effectively interfering with its activation and signaling functions. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Tamoxifen may modulate PKC β activity through indirect pathways, impacting cellular processes that indirectly affect PKC β function. | ||||||
Hesperidin | 520-26-3 | sc-205711 sc-205711A | 25 g 100 g | $80.00 $200.00 | 5 | |
Hesperidin's influence on PKC β is likely indirect, possibly affecting cellular pathways and cascades that indirectly impact PKC β activity. | ||||||