Date published: 2026-5-7

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PISD Activators

PISD activators constitute a specialized category of chemical compounds with a distinct role in the regulation of Phosphatidylserine Decarboxylase (PISD) activity. Phosphatidylserine decarboxylase is a key enzyme involved in the biosynthesis of phospholipids, particularly phosphatidylethanolamine (PE), an essential component of cellular membranes. These activators are meticulously designed to interact with PISD and enhance its enzymatic function, thereby influencing the rate at which phosphatidylserine is converted into phosphatidylethanolamine within cells.

At the molecular level, the mechanisms through which PISD activators exert their effects can be multifaceted. They may involve binding to specific regions of the PISD enzyme, promoting conformational changes that facilitate its catalytic activity. By fine-tuning PISD function, these activators play a pivotal role in cellular membrane remodeling and lipid metabolism. This class of compounds offers invaluable tools for researchers delving into the intricate mechanisms of cellular lipid homeostasis and membrane dynamics. Additionally, understanding PISD activators aids in uncovering the nuances of phospholipid biosynthesis, a fundamental process essential for cell viability and function. By deciphering how these activators modulate PISD, researchers gain critical insights into the regulation of cellular lipid composition, membrane structure, and potentially uncover novel avenues for exploration in cell biology and biochemistry.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rotenone

83-79-4sc-203242
sc-203242A
1 g
5 g
$89.00
$259.00
41
(2)

As a mitochondrial complex I inhibitor, rotenone affects mitochondrial function, which might indirectly influence enzymes like PISD.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$71.00
$184.00
1
(1)

Involved in the electron transport chain in mitochondria, CoQ10 supplementation may influence mitochondrial enzymes, but its effect on PISD is not directly known.

Mdivi-1

338967-87-6sc-215291
sc-215291B
sc-215291A
sc-215291C
5 mg
10 mg
25 mg
50 mg
$67.00
$126.00
$251.00
$465.00
13
(2)

This compound inhibits mitochondrial division, potentially affecting various mitochondrial enzymes. Direct effect on PISD is not documented.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

A compound with various effects including on mitochondrial function. Its direct relationship with PISD is not established.

Oligomycin

1404-19-9sc-203342
sc-203342C
10 mg
1 g
$149.00
$12495.00
18
(2)

As a mitochondrial ATP synthase inhibitor, oligomycin affects mitochondrial function, but its effect on PISD isn't directly known.

2-Deoxy-D-glucose

154-17-6sc-202010
sc-202010A
1 g
5 g
$70.00
$215.00
26
(2)

This glucose analog affects glycolysis and might have indirect effects on mitochondrial function. Direct influence on PISD is not documented.

Antimycin A

1397-94-0sc-202467
sc-202467A
sc-202467B
sc-202467C
5 mg
10 mg
1 g
3 g
$55.00
$63.00
$1675.00
$4692.00
51
(1)

A complex III inhibitor, it affects mitochondrial function. Its direct effect on PISD isn't known.

2-Thenoyltrifluoroacetone

326-91-0sc-251801
5 g
$37.00
1
(1)

As a mitochondrial complex II inhibitor, TTFA affects mitochondrial function, potentially influencing PISD indirectly.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$69.00
$122.00
$212.00
$380.00
$716.00
3
(1)

An antioxidant that plays a role in mitochondrial energy metabolism. Its direct effect on PISD is not known.

Metformin

657-24-9sc-507370
10 mg
$79.00
2
(0)

Metformin activates AMP-activated protein kinase (AMPK) and affects mitochondrial function. Its effect on PISD isn't directly established, but it might influence related pathways.