Date published: 2025-9-5

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pH Indicators

Santa Cruz Biotechnology now offers a broad range of pH Indicators for use in various applications. pH indicators are vital chemical compounds that change color in response to changes in pH, providing a visual representation of the acidity or alkalinity of a solution. In scientific research, these indicators are crucial for experiments requiring precise pH conditions, enabling researchers to maintain and verify the pH of environments in biochemical and chemical reactions. The utility of pH indicators extends across disciplines, including chemistry, environmental science, and molecular biology, where they serve as essential tools for monitoring reactions, studying enzyme activities, and investigating metabolic pathways. The ability to quickly assess pH values with indicators aids in the optimization of conditions for experimental protocols and ensures the reproducibility of results. These indicators are especially important in studies involving biochemical systems where pH can influence the activity and stability of molecules like proteins and nucleic acids. Advances in pH indicator technology have led to the development of more sensitive and selective indicators that can provide real-time, quantifiable data essential for detailed scientific analysis. The diversity of available pH indicators, each with unique transition pH ranges and colors, allows for their application in a variety of experimental scenarios, supporting a broad range of scientific inquiries. These compounds are integral to the toolkit of researchers aiming to explore and manipulate the chemical foundations of biological processes. View detailed information on our available pH Indicators by clicking on the product name.

Items 11 to 20 of 54 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5(6)-Carboxynaphthofluorescein

128724-35-6sc-210424
25 mg
$102.00
(0)

5(6)-Carboxynaphthofluorescein is a versatile pH indicator characterized by its vibrant fluorescence, which shifts in intensity across varying pH levels. This compound features a unique naphthalene core that enables strong π-π stacking interactions, enhancing its stability in solution. Its carboxyl groups facilitate hydrogen bonding, contributing to its sensitivity in detecting subtle pH changes. The compound's distinct photophysical properties allow for real-time monitoring of pH fluctuations.

Benzopurpurine 4B

992-59-6sc-311286
100 g
$200.00
(0)

Benzopurpurine 4B is a synthetic dye known for its striking colorimetric response to pH changes. Its unique structure includes multiple aromatic rings that promote extensive conjugation, resulting in pronounced light absorption and distinct color transitions. The presence of sulfonic acid groups enhances solubility in aqueous environments, while facilitating ionic interactions that influence its spectral properties. This compound exhibits rapid reaction kinetics, making it effective for dynamic pH monitoring.

Bromocresol Green

76-60-8sc-206048
25 g
$158.00
(0)

Bromocresol Green is a pH indicator characterized by its distinctive color shift in response to acidity. Its molecular structure features a brominated cresol backbone, which contributes to its unique electronic properties and stability in various environments. The compound undergoes protonation and deprotonation, leading to significant alterations in its absorption spectrum. This behavior is influenced by hydrogen bonding and hydrophobic interactions, allowing for precise pH detection across a range of conditions.

3′,3″,5′,5″-Tetraiodophenolsulfonephthalein

4430-24-4sc-206023B
sc-206023
1 g
5 g
$153.00
$408.00
(1)

3′,3′′,5′,5′′-Tetraiodophenolsulfonephthalein is a pH indicator notable for its vibrant color transitions, which arise from its complex molecular architecture. The presence of multiple iodine atoms enhances its electron density, facilitating unique charge transfer interactions. This compound exhibits distinct solubility characteristics, allowing it to engage in specific ion-pairing dynamics in solution. Its reaction kinetics are influenced by environmental factors, leading to rapid and reversible color changes that reflect subtle shifts in pH.

5(6)-carboxyfluorescein, mixed isomers

72088-94-9sc-291088
sc-291088A
1 g
5 g
$64.00
$206.00
(0)

5(6)-carboxyfluorescein, mixed isomers, is a versatile pH indicator characterized by its fluorescence properties, which are sensitive to protonation states. The carboxyl groups facilitate hydrogen bonding and ionic interactions, enhancing its solubility in aqueous environments. This compound exhibits a unique dual fluorescence mechanism, where its emission spectrum shifts in response to pH changes, allowing for precise monitoring of acidic and basic conditions. Its dynamic behavior is influenced by local ionic strength and temperature, making it a valuable tool for studying pH-dependent processes.

6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt

61255-63-8sc-210562
100 mg
$177.00
(0)

6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt is a unique compound that exhibits strong solubility in water due to its sulfonic acid groups, which enhance ionic interactions. Its structure allows for effective electron delocalization, contributing to distinct optical properties. The compound's ability to form stable complexes with metal ions can influence reaction kinetics, making it a subject of interest in studies of molecular interactions and environmental chemistry.

Bromothymol Blue

76-59-5sc-206047
sc-206047A
5 g
25 g
$37.00
$130.00
(0)

Bromothymol Blue is a pH indicator characterized by its unique structural features, including a central phenol group that undergoes protonation and deprotonation, leading to distinct color changes across a specific pH range. Its molecular interactions with hydrogen ions facilitate rapid equilibrium shifts, allowing for sensitive detection of acidity. The compound's hydrophobic regions contribute to its solubility dynamics, influencing its behavior in various aqueous environments.

Thymol Blue

76-61-9sc-206049
sc-206049A
5 g
25 g
$31.00
$92.00
2
(0)

Thymol Blue is a versatile pH indicator known for its dual color transitions, which occur at specific pH thresholds. Its unique structure features a sulfonic acid group that enhances solubility in water, promoting effective ionization. The compound exhibits strong interactions with protons, enabling swift shifts in equilibrium that reflect changes in acidity. Additionally, its hydrophilic and hydrophobic characteristics allow it to respond dynamically in diverse chemical environments, making it a reliable indicator for pH monitoring.

Phenolphthalein

77-09-8sc-206050
sc-206050A
100 g
500 g
$39.00
$134.00
1
(1)

Phenolphthalein is a pH indicator characterized by its striking color change from colorless to pink as pH increases, typically around 8.2 to 10.0. Its unique structure allows for effective protonation and deprotonation, leading to rapid equilibrium shifts. The compound's hydrophobic nature contributes to its solubility in organic solvents, facilitating its use in various chemical environments. This behavior highlights its sensitivity to changes in acidity, making it a prominent choice for pH analysis.

Bromocresol Purple

115-40-2sc-205992
sc-205992A
5 g
10 g
$31.00
$46.00
(0)

Bromocresol Purple is a pH indicator that exhibits a vivid color transition from yellow to purple as pH shifts from acidic to neutral. Its unique molecular structure features a sulfonic acid group, enhancing solubility in aqueous solutions. The compound's ability to undergo reversible protonation allows for distinct colorimetric responses, making it particularly effective in detecting subtle pH changes. This dynamic behavior underscores its role in various analytical applications.