PET100 Activators
Chemical activators of PET100 are compounds that can influence mitochondrial biogenesis and function. Enhancing mitochondrial biogenesis or supporting the electron transport chain's function may indirectly impact the expression or functional activity of PET100. Among these activators, AICAR and Metformin stand out due to their roles in activating AMPK, a master regulator of cellular energy homeostasis. The activation of AMPK leads to a cascade of events promoting mitochondrial biogenesis and function, which could support the assembly of COX, the process PET100 is involved in. This indirect activation pathway suggests that any compound enhancing mitochondrial biogenesis or function may contribute to the optimal performance of PET100's role in COX assembly.
Other molecules such as Bezafibrate, Pioglitazone, and Berberine operate through modulation of PPARs and PGC-1α, which are pivotal for the transcriptional control of genes involved in mitochondrial function and biogenesis. Their influence extends to the potential support of PET100 activity by ensuring an environment rich in mitochondrial components and conducive to effective mitochondrial assembly.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AICAR mimics adenosine monophosphate (AMP) and can activate AMP-activated protein kinase (AMPK), which subsequently can enhance mitochondrial biogenesis, possibly impacting PET100's role in COX assembly. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Bezafibrate activates peroxisome proliferator-activated receptors (PPARs), which can lead to the upregulation of mitochondrial biogenesis, potentially affecting PET100 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol activates sirtuin 1 (SIRT1), which can promote mitochondrial biogenesis through the deacetylation of PGC-1α, a regulator of mitochondrial genes that may include those associated with PET100. | ||||||
L-Leucine | 61-90-5 | sc-364173 sc-364173A | 25 g 100 g | $21.00 $61.00 | ||
Leucine can stimulate the mammalian target of rapamycin (mTOR) pathway, which is involved in protein synthesis including mitochondrial proteins, possibly enhancing PET100 expression or function. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
NAD+ precursors can increase the levels of NAD+, which is essential for sirtuin activity and can influence mitochondrial function, potentially affecting PET100 activity indirectly. | ||||||
Metformin-d6, Hydrochloride | 1185166-01-1 | sc-218701 sc-218701A sc-218701B | 1 mg 5 mg 10 mg | $286.00 $806.00 $1510.00 | 1 | |
Metformin activates AMPK, which enhances mitochondrial biogenesis and could indirectly support the role of PET100 in COX assembly. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
Pioglitazone, a PPARγ agonist, can induce mitochondrial biogenesis, potentially impacting the mitochondrial proteins associated with PET100. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Coenzyme Q10 is involved in the electron transport chain; enhancing its activity can increase mitochondrial function, possibly influencing PET100 activity related to COX biogenesis. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
α-Lipoic acid is known to influence mitochondrial biogenesis and could have an indirect effect on PET100 function by affecting overall mitochondrial health and protein assembly. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine can induce autophagy and mitochondrial renewal, which may support PET100 function in new mitochondrial biogenesis. | ||||||