Perp Activators
Perp Activators represents compounds identified to potentially impact the function or expression of the Perp protein, crucial in cellular apoptosis and integral to epidermal structures. Agents such as Nutlin-3, a p53 activator, are known to modulate the activity of p53, a regulator protein, thereby possibly influencing the expression levels of its downstream target, Perp. Similarly, the use of DNA-damaging agents like Doxorubicin can induce alterations in p53 activity, leading to changes in Perp expression. Another approach involves utilizing HDAC inhibitors like Trichostatin A to modify histone acetylation levels, impacting the transcription levels of Perp and, consequently, its expression and function in cellular structures.
Anisomycin can activate the JNK pathways and could influence Perp expression by modulating cellular signaling mechanisms. The introduction of ER stress-inducing agents like Tunicamycin activates pathways that may affect Perp expression levels. Agents like Hydrogen Peroxide and Rapamycin, known to induce ROS and inhibit mTOR signaling respectively, present additional routes to modify Perp expression.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
By activating p53, it can influence the expression of its downstream targets, including Perp. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
DNA damage can induce p53 activity and subsequently influence Perp expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Altering histone acetylation levels may affect the transcription of Perp. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
May influence Perp through modulation of PKC signaling pathways. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
Activating JNK pathways might impact Perp expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
ER stress can lead to the activation of pathways that might influence Perp expression. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Increased ROS levels can activate several signaling pathways impacting Perp expression. | ||||||
4-Nitroquinoline N-oxide | 56-57-5 | sc-256815 sc-256815A | 1 g 5 g | $122.00 $413.00 | 6 | |
By mimicking the effects of UV radiation, it can influence p53 and subsequently Perp expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Influencing mTOR signaling could potentially affect Perp expression. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
By inducing caspase activity, it can potentially influence Perp expression indirectly. | ||||||