Date published: 2025-9-5

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Pepsin Inhibitors

Santa Cruz Biotechnology now offers a broad range of Pepsin Inhibitors for use in various applications. Pepsin Inhibitors are crucial tools for studying the activity and regulation of pepsin, a major digestive enzyme responsible for the breakdown of proteins in the stomach. By inhibiting pepsin, researchers can explore its role in proteolytic processes and understand the mechanisms of protein digestion and degradation. These inhibitors are vital for investigating the specificity and kinetics of pepsin activity, providing insights into its interaction with various substrates and inhibitors. In scientific research, Pepsin Inhibitors are used to study the effects of pepsin activity on various physiological processes, including nutrient absorption and gastrointestinal function. Researchers employ these inhibitors to dissect the pathways involved in protein metabolism and to understand how the inhibition of pepsin affects overall digestive processes. Additionally, Pepsin Inhibitors are utilized in the study of protein structure and function, as they allow scientists to stabilize protein samples by preventing proteolysis during experimental procedures. These inhibitors also play a role in exploring the evolutionary aspects of digestive enzymes by comparing the activity and inhibition of pepsin across different species. The use of Pepsin Inhibitors supports the development of new research methodologies and enhances our understanding of digestive enzyme regulation and function. View detailed information on our available Pepsin Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pepstatin A

26305-03-3sc-45036
sc-45036A
sc-45036B
5 mg
25 mg
500 mg
$60.00
$185.00
$1632.00
50
(4)

Pepstatin A is a potent inhibitor of pepsin, characterized by its ability to form stable complexes with the enzyme, effectively blocking substrate access. This interaction is facilitated by specific hydrogen bonding and hydrophobic contacts, which alter the enzyme's active site conformation. The kinetics of this inhibition reveal a competitive mechanism, where Pepstatin A's presence significantly reduces pepsin's catalytic efficiency, impacting protein digestion pathways. Its unique structural features contribute to its specificity and effectiveness in modulating proteolytic activity.