Date published: 2025-9-29

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PDH-E1 Antibodies

Santa Cruz Biotechnology features a diverse variety of PDH-E1 monoclonal antibodies for research focused on understanding the pyruvate dehydrogenase complex in cellular metabolism. PDH-E1 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PDH-E1 serves as a crucial component of the pyruvate dehydrogenase complex, catalyzing the conversion of pyruvate into acetyl-CoA, which connects glycolysis to the citric acid cycle. This conversion process plays a fundamental role in energy production and metabolic regulation within cells. Abnormal PDH-E1 function can result in metabolic disorders and is associated with various diseases, including cancer and neurodegenerative conditions. Understanding PDH-E1's role in metabolism has become increasingly important in both basic research and therapeutic development. Investigating PDH-E1 function helps reveal the complexities of cellular energy production and its impact on various physiological processes. Research utilizing PDH-E1 monoclonal antibodies continues to advance our knowledge of metabolic regulation and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of cellular metabolism and its role in health and disease.

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PDH-E1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PDH-E1α Antibody (D-6)

sc-377092mouse IgG2a κ31-161 (h)WB, IP, IF, IHC(P), ELISAm, r, h
76
(15)

PDH-E1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDH-E1α CRISPR/Cas9 KO Plasmid (h)

sc-401044hGene KnockoutGFP0
(0)

PDH-E1α HDR Plasmid (h)

sc-401044-HDRhHomology Directed RepairPuromycin0
(0)

PDH-E1α Double Nickase Plasmid (h)

sc-401044-NIChGene KnockoutPuromycin0
(0)

PDH-E1α Double Nickase Plasmid (h2)

sc-401044-NIC-2hGene KnockoutPuromycin0
(0)

PDH-E1α CRISPR/Cas9 KO Plasmid (m)

sc-422172mGene KnockoutGFP0
(0)

PDH-E1α HDR Plasmid (m)

sc-422172-HDRmHomology Directed RepairPuromycin0
(0)

PDH-E1α Double Nickase Plasmid (m)

sc-422172-NICmGene KnockoutPuromycin0
(0)

PDH-E1α Double Nickase Plasmid (m2)

sc-422172-NIC-2mGene KnockoutPuromycin0
(0)

PDH-E1β CRISPR/Cas9 KO Plasmid (h)

sc-408456hGene KnockoutGFP0
(0)

PDH-E1β HDR Plasmid (h)

sc-408456-HDRhHomology Directed RepairPuromycin0
(0)

PDH-E1β Double Nickase Plasmid (h)

sc-408456-NIChGene KnockoutPuromycin0
(0)

PDH-E1β Double Nickase Plasmid (h2)

sc-408456-NIC-2hGene KnockoutPuromycin0
(0)

PDH-E1β CRISPR/Cas9 KO Plasmid (m)

sc-426992mGene KnockoutGFP0
(0)

PDH-E1β HDR Plasmid (m)

sc-426992-HDRmHomology Directed RepairPuromycin0
(0)

PDH-E1β Double Nickase Plasmid (m)

sc-426992-NICmGene KnockoutPuromycin0
(0)

PDH-E1β Double Nickase Plasmid (m2)

sc-426992-NIC-2mGene KnockoutPuromycin0
(0)

PDH-E1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDH-E1α CRISPR Activation Plasmid (h)

sc-401044-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α CRISPR Activation Plasmid (h2)

sc-401044-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α Lentiviral Activation Particles (h)

sc-401044-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α Lentiviral Activation Particles (h2)

sc-401044-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α CRISPR Activation Plasmid (m)

sc-422172-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α CRISPR Activation Plasmid (m2)

sc-422172-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α Lentiviral Activation Particles (m)

sc-422172-LACmGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1α Lentiviral Activation Particles (m2)

sc-422172-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β CRISPR Activation Plasmid (h)

sc-408456-ACThGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β CRISPR Activation Plasmid (h2)

sc-408456-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β Lentiviral Activation Particles (h)

sc-408456-LAChGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β Lentiviral Activation Particles (h2)

sc-408456-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β CRISPR Activation Plasmid (m)

sc-426992-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β CRISPR Activation Plasmid (m2)

sc-426992-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β Lentiviral Activation Particles (m)

sc-426992-LACmGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1β Lentiviral Activation Particles (m2)

sc-426992-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PDH-E1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PDH-E1α siRNA (h)

sc-91064hGene SilencingN/A
3
(0)

PDH-E1α shRNA Plasmid (h)

sc-91064-SHhGene SilencingPuromycin
3
(0)

PDH-E1α shRNA (h) Lentiviral Particles

sc-91064-VhGene SilencingPuromycin
3
(0)

PDH-E1α siRNA (m)

sc-77407mGene SilencingN/A0
(0)

PDH-E1α shRNA Plasmid (m)

sc-77407-SHmGene SilencingPuromycin0
(0)

PDH-E1α shRNA (m) Lentiviral Particles

sc-77407-VmGene SilencingPuromycin0
(0)

PDH-E1β siRNA (h)

sc-77999hGene SilencingN/A0
(0)

PDH-E1β shRNA Plasmid (h)

sc-77999-SHhGene SilencingPuromycin0
(0)

PDH-E1β shRNA (h) Lentiviral Particles

sc-77999-VhGene SilencingPuromycin0
(0)

PDH-E1β siRNA (m)

sc-152135mGene SilencingN/A0
(0)

PDH-E1β shRNA Plasmid (m)

sc-152135-SHmGene SilencingPuromycin0
(0)

PDH-E1β shRNA (m) Lentiviral Particles

sc-152135-VmGene SilencingPuromycin0
(0)