Date published: 2025-12-10

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PCCB Antibodies

Santa Cruz Biotechnology delivers a wide array of PCCB monoclonal antibodies for advanced research in biochemistry and molecular biology. PCCB monoclonal antibodies support multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PCCB, or propionyl-CoA carboxylase beta subunit, plays a crucial role in the metabolism of certain amino acids and fatty acids, particularly in the conversion of propionyl-CoA to methylmalonyl-CoA. PCCB maintains metabolic homeostasis, and deficiencies can lead to metabolic disorders such as propionic acidemia. Understanding PCCB function and regulation is vital for developing therapeutic strategies for metabolic conditions. Researchers worldwide utilize PCCB monoclonal antibodies to investigate metabolic pathways and their impact on human health. Advanced detection methods, including fluorescent conjugates like phycoerythrin (PE) and fluorescein isothiocyanate (FITC), enable precise visualization of PCCB in cellular studies. Horseradish peroxidase (HRP) conjugates provide sensitive detection in various experimental settings. Santa Cruz Biotechnology monoclonal antibodies for PCCB research continue to advance our understanding of metabolic disorders and potential therapeutic interventions.

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PCCB Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PCCB Antibody (E-12)

sc-393929mouse IgG2a κ240-539 (h)WB, IP, IF, ELISAh
2
(4)

PCCB Antibody (E-7)

sc-515741mouse IgG2b κ281-302 (h)WB, IP, IF, ELISAm, r, h

new

(0)

PCCB Antibody (F-6)

sc-515740mouse IgG1 κ281-302 (h)WB, IP, IF, ELISAm, r, h

new

(0)

PCCB CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PCCB CRISPR/Cas9 KO Plasmid (h)

sc-408758hGene KnockoutGFP0
(0)

PCCB HDR Plasmid (h)

sc-408758-HDRhHomology Directed RepairPuromycin0
(0)

PCCB Double Nickase Plasmid (h)

sc-408758-NIChGene KnockoutPuromycin0
(0)

PCCB Double Nickase Plasmid (h2)

sc-408758-NIC-2hGene KnockoutPuromycin0
(0)

PCCB CRISPR/Cas9 KO Plasmid (m)

sc-426258mGene KnockoutGFP0
(0)

PCCB HDR Plasmid (m)

sc-426258-HDRmHomology Directed RepairPuromycin0
(0)

PCCB Double Nickase Plasmid (m)

sc-426258-NICmGene KnockoutPuromycin0
(0)

PCCB Double Nickase Plasmid (m2)

sc-426258-NIC-2mGene KnockoutPuromycin0
(0)

PCCB CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PCCB CRISPR Activation Plasmid (h)

sc-408758-ACThGene ActivationPuro, Blast, Hygro0
(0)

PCCB CRISPR Activation Plasmid (h2)

sc-408758-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PCCB Lentiviral Activation Particles (h)

sc-408758-LAChGene ActivationPuro, Blast, Hygro0
(0)

PCCB Lentiviral Activation Particles (h2)

sc-408758-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PCCB CRISPR Activation Plasmid (m)

sc-426258-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PCCB CRISPR Activation Plasmid (m2)

sc-426258-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PCCB Lentiviral Activation Particles (m)

sc-426258-LACmGene ActivationPuro, Blast, Hygro0
(0)

PCCB Lentiviral Activation Particles (m2)

sc-426258-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PCCB siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PCCB siRNA (h)

sc-76079hGene SilencingN/A0
(0)

PCCB shRNA Plasmid (h)

sc-76079-SHhGene SilencingPuromycin0
(0)

PCCB shRNA (h) Lentiviral Particles

sc-76079-VhGene SilencingPuromycin0
(0)

PCCB siRNA (m)

sc-76080mGene SilencingN/A0
(0)

PCCB shRNA Plasmid (m)

sc-76080-SHmGene SilencingPuromycin0
(0)

PCCB shRNA (m) Lentiviral Particles

sc-76080-VmGene SilencingPuromycin0
(0)