PAP-2d Activators
PAP-2d Activators constitute a specialized category of chemical compounds or molecules that have garnered interest within the field of molecular biology and cellular research. These activators are designed or discovered with the specific aim of modulating the activity of PAP-2d, an enzyme encoded by the PAP2D gene. PAP-2d, or Phosphatidic Acid Phosphatase Type 2 Domain Containing, belongs to the family of phosphatidic acid phosphatases, which play crucial roles in lipid metabolism and cellular membrane dynamics.
The study of PAP-2d activators is intriguing because it enables researchers to delve into the precise role of this enzyme in cellular physiology and molecular mechanisms related to lipid metabolism and membrane homeostasis. Activation of PAP-2d can offer valuable insights into its involvement in the regulation of phosphatidic acid levels, a lipid molecule with diverse cellular functions. By manipulating the activity of PAP-2d through these activators, scientists aim to gain a deeper understanding of the complex molecular pathways and cellular functions that rely on the enzyme's activity, thereby contributing to the broader knowledge of lipid metabolism and cellular membrane dynamics. Consequently, PAP-2d activators serve as valuable tools for researchers dedicated to unraveling the intricate molecular mechanisms that govern cellular biology, particularly within the context of lipid metabolism and membrane physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC) which may indirectly upregulate PLPPR5 expression through modulation of lipid signaling pathways. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid regulates gene expression through nuclear receptors and could potentially increase expression of lipid metabolism-related genes like PLPPR5. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methylation inhibitor, 5-azacytidine can alter gene expression patterns, potentially upregulating PLPPR5. | ||||||
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $28.00 $88.00 $332.00 | 12 | |
Lovastatin inhibits HMG-CoA reductase, potentially upregulating lipid-related genes, including PLPPR5, to compensate for cholesterol synthesis inhibition. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
As a PPAR-gamma agonist, pioglitazone modulates lipid metabolism and could influence PLPPR5 expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin alters various signaling pathways and could modulate expression of genes involved in lipid metabolism, such as PLPPR5. | ||||||
Choline chloride | 67-48-1 | sc-207430 sc-207430A sc-207430B | 10 mg 5 g 50 g | $32.00 $36.00 $51.00 | 1 | |
Choline is involved in phospholipid synthesis, and its availability could potentially upregulate related enzymes like PLPPR5. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Nicotinamide, a form of vitamin B3, participates in cellular metabolism and could indirectly affect PLPPR5 expression. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
S1P is a bioactive lipid that modulates signaling pathways, potentially influencing PLPPR5 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin increases intracellular cAMP levels, which can modulate gene expression, possibly affecting PLPPR5. | ||||||