PAMCI Activators

Ras association domain family member 9 (RASSF9) is a protein that belongs to the RASSF family, which is known for its involvement in important cellular processes such as cell cycle control, apoptosis, and maintenance of genomic stability. The RASSF proteins typically interact with Ras GTPases, which are molecular switches that regulate a wide array of signaling networks controlling cell proliferation, differentiation, and survival.

RASSF9 contains a Ras association (RA) domain, which is indicative to bind Ras proteins and thereby influence Ras-mediated signaling pathways. While the specific functions of RASSF9 are not as extensively studied as other family members, it is believed to contribute to the modulation of these critical pathways, possibly impacting cell growth and apoptosis.The expression of RASSF9 is thought to be regulated by various intracellular signaling cascades and could be responsive to changes in the cellular environment that affect Ras signaling. Given the pivotal role of Ras in oncogenesis, proteins like RASSF9 that interact with the Ras pathway are of significant interest for their role in cancer biology.