PABPC6 Inhibitors
Common PABPC6 Inhibitors include, but are not limited to Cordycepin CAS 73-03-0, Aurintricarboxylic Acid CAS 4431-00-9, C646 CAS 328968-36-1, CCG-1423 CAS 285986-88-1 and Ribavirin CAS 36791-04-5.
PABPC6 inhibitors form a distinctive category of chemical compounds designed to interact with and modulate the function of the poly(A)-binding protein cytoplasmic 6 (PABPC6). PABPC6 is a member of the poly(A)-binding protein family, which plays a crucial role in post-transcriptional gene regulation by binding to the poly(A) tail of mRNA molecules. This binding facilitates mRNA stability, translation initiation, and other aspects of mRNA metabolism. Inhibitors tailored for PABPC6 are developed with the intent of targeting specific binding sites within the protein's structure, influencing its interaction with mRNA and translation-related factors.
The interaction between PABPC6 inhibitors and the PABPC6 protein offers a valuable avenue for studying the intricacies of mRNA regulation and translation. By selectively modulating the interaction between PABPC6 and mRNA, these inhibitors provide a tool to dissect the mechanisms through which mRNA stability and translation initiation are controlled. The investigation of PABPC6 inhibitors contributes to a deeper understanding of the molecular processes that underlie gene expression, translation, and cellular responses to various stimuli. This chemical class enhances our insight into the regulatory mechanisms governing mRNA metabolism and the dynamic interplay between mRNA, translation factors, and cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cordycepin | 73-03-0 | sc-203902 | 10 mg | $101.00 | 5 | |
Cordycepin might inhibit PABP indirectly by affecting mRNA stability and translation through interference with polyadenylation. | ||||||
A-485 | 1889279-16-6 | sc-507493 | 5 mg | $275.00 | ||
A-485 is a selective inhibitor of PABPC1, a member of the PABP family, potentially impacting mRNA translation and stability. | ||||||
Aurintricarboxylic Acid | 4431-00-9 | sc-3525 sc-3525A sc-3525B sc-3525C | 100 mg 1 g 5 g 10 g | $20.00 $32.00 $48.00 $94.00 | 13 | |
Aurintricarboxylic acid might interfere with PABP binding to mRNA, potentially affecting mRNA stability and translation. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
C646 is a histone acetyltransferase inhibitor that might affect PABP indirectly through its impact on gene expression and mRNA stability. | ||||||
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
CCG-1423 is a Rho pathway inhibitor that might indirectly impact PABP through its effects on cytoskeletal dynamics and mRNA transport. | ||||||
Ribavirin | 36791-04-5 | sc-203238 sc-203238A sc-203238B | 10 mg 100 mg 5 g | $63.00 $110.00 $214.00 | 1 | |
Ribavirin might indirectly impact PABP by affecting mRNA stability and translation, particularly in the context of viral infections. | ||||||
Chitosan | 9012-76-4 | sc-221421 sc-221421A sc-221421B sc-221421D sc-221421C | 10 g 25 g 100 g 8 kg 500 g | $41.00 $55.00 $135.00 $3339.00 $298.00 | 6 | |
Chitosan might indirectly impact PABP by affecting mRNA stability and translation through its interactions with nucleic acids. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
Neomycin might affect PABP indirectly by interfering with RNA structure and interactions, potentially impacting mRNA translation and stability. | ||||||