Date published: 2025-10-29

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p55 Inhibitors

p55 inhibitors are a class of chemical compounds that have garnered interest in the fields of molecular biology and modulate specific cellular processes. p55, also known as p55CDC, is a regulatory protein that plays a crucial role in cell division and the cell cycle. Specifically, it is associated with the regulation of the cell cycle at the G2/M transition, ensuring the proper progression of cells from the G2 phase to mitosis. p55 is involved in interactions with various cellular proteins, including cyclin-dependent kinases (CDKs) and checkpoint proteins, to coordinate cell cycle progression and maintain genomic stability. p55 inhibitors are designed to interact with the active site or binding domain of the p55 protein, effectively inhibiting its function and influencing cellular processes dependent on p55-mediated cell cycle regulation.

Structurally, p55 inhibitors are engineered to selectively target the active site or binding domains of p55, ensuring high specificity for this particular regulatory protein. By inhibiting p55, these compounds may disrupt its role in coordinating the G2/M transition of the cell cycle, leading to defects in cell division and genomic instability. The study of p55 inhibitors is of significant interest to researchers as it provides insights into the regulatory mechanisms governing essential cellular functions related to cell cycle control and DNA replication. This knowledge contributes to our understanding of basic cell biology and may have implications in various research areas, including cancer biology, cell proliferation disorders, and the molecular basis of diseases associated with abnormal cell cycle regulation. However, further research is required to fully explore the extent of their applications and their impact on cellular physiology in the context of p55-mediated cell cycle regulation.

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