P2Y1 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
NF 449 | 389142-38-5 | sc-203159 | 10 mg | $314.00 | 5 | |
NF 449 is a selective P2Y1 receptor antagonist, distinguished by its unique binding affinity that disrupts ATP-mediated signaling. This compound exhibits a high degree of specificity, effectively blocking receptor activation and subsequent intracellular calcium influx. Its structural features allow for distinct molecular interactions, influencing receptor conformation and inhibiting downstream signaling pathways. The compound's kinetic properties enable it to modulate receptor activity with precision, making it a valuable tool for studying purinergic signaling dynamics. | ||||||
Adenosine 2′,5′-diphosphate sodium salt | 154146-84-6 | sc-214495 sc-214495A | 5 mg 25 mg | $160.00 $530.00 | 2 | |
Adenosine 2',5'-diphosphate sodium salt serves as a potent agonist for the P2Y1 receptor, facilitating the activation of G-protein coupled pathways. Its unique phosphate group arrangement enhances binding affinity, promoting receptor conformational changes that trigger intracellular signaling cascades. The compound's rapid kinetics allow for swift modulation of cellular responses, influencing platelet aggregation and vascular functions. Its distinct molecular interactions underscore its role in purinergic signaling networks. | ||||||
MRS 2179 ammonium salt | 101204-49-3 | sc-253058 | 5 mg | $313.00 | 1 | |
MRS2179 selectively antagonizes P2Y1 by blocking the binding of ADP, thereby potentially reducing P2Y1-mediated responses. | ||||||
PPADS tetrasodium salt | 192575-19-2 | sc-253332 sc-253332A | 10 mg 50 mg | $101.00 $376.00 | 2 | |
PPADS tetrasodium salt acts as a selective antagonist for the P2Y1 receptor, effectively inhibiting its activation. The compound's unique structure allows it to disrupt the binding of endogenous nucleotides, altering receptor dynamics and downstream signaling pathways. Its high affinity for the receptor ensures prolonged interaction, impacting the kinetics of purinergic signaling. This modulation can influence various cellular processes, highlighting its role in regulating physiological responses. | ||||||
2-Methylthio-ADP trisodium salt | 475193-31-8 | sc-203464 | 10 mg | $838.00 | 5 | |
2-MeSADP, though an agonist, upon chronic exposure could lead to P2Y1 downregulation, which indirectly inhibits its expression. | ||||||
Ticagrelor | 274693-27-5 | sc-472972 sc-472972A sc-472972B sc-472972C | 10 mg 25 mg 50 mg 100 mg | $104.00 $228.00 $270.00 $302.00 | ||
Ticagrelor has the capability to inhibit the P2Y1 receptor, among others, which could diminish platelet aggregation pathways. | ||||||
Prasugrel | 150322-43-3 | sc-391536 | 100 mg | $79.00 | ||
Prasugrel metabolites may inhibit P2Y1 receptor activity, potentially affecting platelet function regulation. | ||||||