p21 Activators
Items 1 to 10 of 13 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tenovin-1 | 380315-80-0 | sc-222342 | 10 mg | $87.00 | 1 | |
Tenovin-1 is a small molecule characterized by its ability to modulate cellular pathways through the activation of p21, a cyclin-dependent kinase inhibitor. Its unique structure allows for selective interactions with key regulatory proteins, influencing cell cycle progression. The compound exhibits distinct kinetic properties, promoting rapid binding to target sites, which can alter downstream signaling cascades. Additionally, its hydrophobic characteristics enhance membrane permeability, facilitating cellular uptake. | ||||||
Hygrolidin | 83329-73-1 | sc-391768 sc-391768A sc-391768B sc-391768C | 1 mg 5 mg 10 mg 25 mg | $332.00 $1300.00 $1900.00 $3749.00 | ||
Hygrolidin is a distinctive compound that acts as a p21 modulator, engaging in specific interactions with cellular machinery to influence gene expression. Its unique structural features enable it to stabilize protein conformations, thereby affecting the dynamics of cell cycle regulation. The compound demonstrates notable reaction kinetics, with a propensity for rapid association and dissociation with target proteins, which can lead to significant alterations in cellular signaling networks. Its amphiphilic nature enhances its interaction with lipid membranes, promoting effective cellular integration. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a natural polyphenol found in grapes and red wine. It activates p21 by inhibiting histone deacetylases (HDACs), leading to increased p21 expression and cell cycle arrest. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, found in turmeric, can activate p21 through multiple pathways, including the upregulation of p53 and inhibition of NF-κB, resulting in enhanced p21 expression and cell cycle regulation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, induces p21 expression by promoting the nuclear translocation of Nrf2 and subsequent binding to the p21 promoter region. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, abundant in green tea, activates p21 by modulating several signaling pathways, including PI3K/AKT and MAPK, leading to cell cycle arrest and apoptosis. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin can activate p21 through its antioxidant properties and by inhibiting cyclin-dependent kinases (CDKs), resulting in cell cycle arrest and p21 upregulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, found in soy products, activates p21 by inhibiting CDKs and inducing p53, leading to cell cycle arrest and increased p21 expression. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Indole-3-carbinol, present in cruciferous vegetables, can activate p21 by modulating estrogen metabolism and promoting cell cycle arrest. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid activates p21 through its interaction with retinoic acid receptors (RARs), leading to cell differentiation and p21 upregulation in certain cell types. | ||||||