OTTMUSG00000014164 Activators

Olfactory receptor 1506-like isoform X1, encoded by the Gm13769 gene, plays a pivotal role in the sense of smell, specifically in the detection and discrimination of various odorants. This receptor is a member of a large family of G-protein coupled receptors (GPCRs) located in the olfactory sensory neurons of the nasal epithelium. These receptors are responsible for detecting volatile molecules in the environment, allowing organisms to perceive and identify different odors. The activation of Gm13769 primarily occurs through the binding of odorant molecules to specific receptor sites within the olfactory sensory neurons. When an odorant, such as eugenol, isoamyl acetate, or limonene, interacts with the receptor, it triggers a cascade of events. This includes the activation of G-proteins, which subsequently initiates intracellular signaling pathways. Ultimately, these processes lead to the generation of electrical signals that are transmitted to the brain, where odor perception and discrimination take place.

The specificity and sensitivity of Gm13769 in detecting various odorants are critical for our ability to discern a wide range of scents in our environment. The direct activation of this receptor by specific chemicals, as outlined in the table, allows for the recognition and interpretation of distinct odors, contributing to our sense of smell and our ability to interact with the world through olfaction. In conclusion, olfactory receptor 1506-like isoform X1 (Gm13769) is a key player in our olfactory system, enabling us to perceive and differentiate a multitude of odors in our surroundings. Its activation is initiated by the binding of odorant chemicals to receptor sites, leading to the intricate processes of olfactory signal transduction and odor perception. This molecular mechanism underlies our ability to experience the rich tapestry of scents in the world around us.