Date published: 2026-2-22

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OR5T3 Activators

OR5T3 engage with this olfactory receptor in a variety of ways, each utilizing a unique molecular interaction to initiate signal transduction. Acetylcholine, for instance, activates OR5T3 due to its role as a neurotransmitter in olfactory signaling, where it binds to olfactory sensory neurons and leads to the activation of this specific olfactory receptor. Similarly, menthol targets OR5T3 by binding to its ligand-specific domain, causing a conformational change that triggers the signaling cascade. Eugenol, another activator, interacts with OR5T3's ligand-binding domain, which precipitates a series of signaling events within the olfactory system. Isoamyl acetate, known for its characteristic fruity scent, also activates OR5T3 through direct receptor binding, resulting in the activation of olfactory signal transduction pathways.

Anethole and geraniol both serve as activators of OR5T3 by docking at the receptor's binding site, thereby inducing a signaling response characteristic of olfactory perception. Citral, with its ability to bind to olfactory receptors including OR5T3, alters the receptor's configuration and sets off downstream signaling. Limonene follows a similar activation pattern, directly influencing OR5T3 and engaging the olfactory sensory pathways. Benzaldehyde and cinnamaldehyde both activate OR5T3 by binding interactions, which initiate the signaling mechanisms essential for olfactory detection. Additionally, ethyl vanillin and methyl salicylate activate OR5T3 by directly interacting with its ligand-binding domain, thereby inducing the signaling pathways that underpin the olfactory system's functional response. Each of these chemicals, by binding to OR5T3, plays a crucial role in the nuanced processes of olfactory perception.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(±)-Menthol

89-78-1sc-250299
sc-250299A
100 g
250 g
$39.00
$68.00
(0)

Menthol is known to bind to and activate certain olfactory receptors. Given that OR5T3 is an olfactory receptor, menthol can activate OR5T3 by binding to its ligand-specific domain, causing a conformational change and initiating signal transduction.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$32.00
$62.00
$218.00
2
(1)

Eugenol activates olfactory receptors by binding to the receptor sites. As OR5T3 is an olfactory receptor, eugenol can activate OR5T3 by direct interaction with its ligand-binding domain, which triggers downstream signaling cascades.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$107.00
$225.00
(0)

Isoamyl acetate, a compound known for its fruity odor, activates olfactory receptors. It activates OR5T3 by binding directly to the receptor, which in turn induces a signal transduction pathway specific to olfactory signaling.

Anethole

104-46-1sc-481571A
sc-481571
10 g
100 g
$576.00
$316.00
(0)

Anethole is a compound recognized by olfactory receptors, and it activates OR5T3 by interacting with the receptor's binding site, initiating a signaling cascade that leads to the functional response associated with olfaction.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$45.00
$119.00
(0)

Geraniol activates olfactory receptors by binding to their specific detection sites. OR5T3, being part of this receptor family, is activated by geraniol through ligand-receptor interaction, which promotes olfactory signal transduction.

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

Citral is known to activate olfactory receptors, and as such, it activates OR5T3 by direct binding, which then causes a signaling cascade that leads to the activation of olfactory sensory pathways.

D-Limonene

5989-27-5sc-205283
sc-205283A
100 ml
500 ml
$84.00
$129.00
3
(1)

Limonene activates olfactory receptors and thus activates OR5T3 by interacting directly with it, causing a change in conformation and initiating the downstream signaling required for olfactory perception.

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$104.00
$228.00
(0)

Cinnamaldehyde activates the OR5T3 protein by binding to the olfactory receptor, which is part of the G-protein coupled receptor family, and triggers a signaling cascade that results in olfactory perception.

3-Ethoxy-4-hydroxybenzaldehyde

121-32-4sc-238538
100 g
$31.00
(0)

3-Ethoxy-4-hydroxybenzaldehyde activates olfactory receptors by binding to them. It activates OR5T3 by direct interaction with its ligand-binding domain, inducing the activation of the signaling pathways responsible for olfactory detection.

Methyl Salicylate

119-36-8sc-204802
sc-204802A
250 ml
500 ml
$47.00
$70.00
(1)

Methyl salicylate is known to activate olfactory receptors, and it activates OR5T3 through direct binding to the receptor, which in turn activates the associated signaling pathways for olfactory function.