OR51F2_Olfr568 Activators
OR51F2 engage with the olfactory receptor in a manner that initiates a cascade of intracellular events, leading to the cellular responses characteristic of scent detection. Isopentyl acetate, for instance, binds to OR51F2, inducing a conformational change in the receptor and triggering the G-protein coupled receptor (GPCR) pathway. This activation results in a series of downstream effects including the production of cyclic AMP (cAMP), a secondary messenger that amplifies the signal within the olfactory sensory neurons. Similarly, amyl butyrate acts as an agonist to OR51F2, thereby initiating the olfactory signaling pathway, which involves the activation of adenylyl cyclase and a subsequent rise in cAMP levels. Propyl hexanoate and heptanal also function as agonists, binding directly to OR51F2 and leading to an increase in intracellular calcium levels and the production of inositol triphosphate (IP3) and diacylglycerol (DAG), both of which play a role in the signaling pathways of olfactory perception.
Methyl salicylate and benzaldehyde activate OR51F2 by binding to the receptor, which triggers the GPCR signaling cascade effectuating the perception of scent. Ethyl butyrate and octanal, when bound to OR51F2, lead to the activation of phospholipase C and a rise in intracellular calcium, which are indicative of the receptor's activation. 1-Octen-3-ol and 2-phenylethanol engage OR51F2 by binding to the active site and extracellular domain, respectively, both resulting in the triggering of the G-protein signaling cascade within olfactory sensory neurons. Lastly, geranyl acetate and citronellol activate OR51F2 by binding to the receptor, thus promoting the activation of the olfactory signal transduction pathway, which includes a variety of cellular responses to amplify the signal that is ultimately perceived as scent. Each of these chemicals, through their interaction with OR51F2, elucidates the versatile nature of this receptor in recognizing and responding to a wide spectrum of odorant molecules.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate is known to activate OR51F2 by binding to the odorant receptor, which leads to a conformational change and activation of the G-protein coupled receptor pathway, initiating a signal transduction cascade that results in cellular responses. | ||||||
Heptaldehyde | 111-71-7 | sc-250089 sc-250089A | 2 ml 100 ml | $30.00 $59.00 | ||
Heptanal can activate OR51F2 olfactory receptor by directly interacting with the receptor's binding site, triggering the G-protein signaling cascade that results in the production of inositol triphosphate (IP3) and diacylglycerol (DAG). | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates OR51F2 through direct binding to the receptor, which induces a change in receptor conformation and subsequent activation of the olfactory signal transduction pathway, leading to the perception of scent. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates OR51F2 by functioning as a ligand for the receptor, binding to it and triggering a signaling pathway that leads to a cellular response characteristic of olfactory receptors' activation. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal is an activator of OR51F2, as it binds to the receptor and causes activation of the G-protein coupled receptor signaling pathway, which includes activation of phospholipase C and a subsequent rise in intracellular calcium. | ||||||
1-Octen-3-ol | 3391-86-4 | sc-237604 | 25 g | $50.00 | ||
1-Octen-3-ol activates OR51F2 by binding to the receptor's active site and inducing a conformational change that leads to the activation of olfactory signaling mechanisms within the sensory neuron. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol activates OR51F2 by interacting with the receptor's extracellular domain, which triggers an intracellular G-protein signaling cascade that culminates in the activation of the receptor's function. | ||||||
Geranyl acetate | 105-87-3 | sc-235243 | 25 g | $41.00 | ||
Geranyl acetate activates OR51F2 through binding to the olfactory receptor, promoting the G-protein coupled receptor pathway activation and resulting in the amplification of the olfactory signal. | ||||||
(±)-beta-Citronellol | 106-22-9 | sc-294094 sc-294094A | 25 ml 500 ml | $32.00 $156.00 | ||
Citronellol activates OR51F2 by serving as a specific ligand, directly engaging with the receptor and initiating the signaling pathway that leads to activation of the olfactory signal transduction processes. | ||||||