Date published: 2026-2-22

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OR4C12 Activators

OR4C12 can induce a range of structural changes and interactions that lead to the activation of this olfactory receptor. Oleic Acid, a monounsaturated fatty acid, integrates into cell membranes, potentially enhancing the fluidity of the membrane housing OR4C12 and facilitating the receptor's exposure to activating ligands. Sodium Benzoate, capable of traversing cell membranes, may alter intracellular pH, inducing conformational changes in OR4C12 that favor ligand binding and activation. Methyl Eugenol and Eugenol are phenolic compounds that can directly bind to and activate OR4C12, acting as agonists that initiate signal transduction. Similarly, Citral and Geraniol, compounds found in plant oils, are natural ligands for olfactory receptors and can directly interact with OR4C12, leading to its activation. Isoamyl Acetate, known for its characteristic fruity odor, may also serve as a direct ligand, engaging with OR4C12 and activating it.

Anethole, Skatole, and Farnesol are aromatic compounds that can activate olfactory receptors by directly binding to them, suggesting they engage OR4C12 in a similar manner. Benzaldehyde, with its almond-like aroma, is another chemical that activates olfactory receptors, likely including OR4C12, through direct ligand-receptor interaction. Lastly, Cyclotene or Maple Lactone, recognized for its flavor attributes, can also act as an activator of olfactory receptors, indicating its possible direct interaction with OR4C12. These various chemicals, through their unique molecular interactions, can lead to the activation of OR4C12, initiating the intricate signaling pathways that underpin olfactory perception.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$37.00
$104.00
$580.00
$1196.00
10
(1)

Oleic Acid, a monounsaturated fatty acid, integrates into cell membranes, enhancing membrane fluidity, which may increase the accessibility of OR4C12 to its ligands, thereby facilitating the activation of OR4C12.

Sodium benzoate

532-32-1sc-251009
250 g
$21.00
(1)

Sodium Benzoate is known to pass through cell membranes and can alter intracellular pH. A change in pH can lead to conformational changes in proteins, potentially leading to the activation of OR4C12 by promoting ligand binding affinity.

4-Allyl-1,2-dimethoxybenzene

93-15-2sc-232373
sc-232373A
sc-232373B
5 g
25 g
100 g
$24.00
$42.00
$125.00
(0)

4-Allyl-1,2-dimethoxybenzene interacts with olfactory receptors and has been shown to activate specific olfactory receptor subtypes, which could lead to the activation of OR4C12 by direct binding as a ligand.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$32.00
$62.00
$218.00
2
(1)

Eugenol is a phenolic compound that can bind to and activate certain olfactory receptors. Binding of Eugenol to OR4C12 may lead to its activation by acting as an agonist.

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

Citral, a component found in the oils of several plants, is known to bind to and activate specific olfactory receptors, which suggests that it may activate OR4C12 by direct binding as an olfactory ligand.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$45.00
$119.00
(0)

Geraniol, a monoterpenoid and an alcohol, is a natural compound that can serve as a ligand for olfactory receptors. It may activate OR4C12 by binding directly to the receptor and causing a conformational change that leads to signal transduction.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$107.00
$225.00
(0)

Isoamyl Acetate is an ester known for its fruity odor and is used to test the functionality of olfactory receptors. It could activate OR4C12 directly by binding to the receptor as a ligand.

Anethole

104-46-1sc-481571A
sc-481571
10 g
100 g
$576.00
$316.00
(0)

Anethole is an aromatic compound that can activate certain olfactory receptors, suggesting it may activate OR4C12 through direct ligand-receptor interaction.

Farnesol

4602-84-0sc-204748
sc-204748A
50 ml
100 ml
$281.00
$374.00
2
(1)

Farnesol, a natural 15-carbon organic compound, has a role in the activation of some olfactory receptors. It may activate OR4C12 by binding as a ligand and triggering receptor-mediated signaling pathways.