Date published: 2025-12-24

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OR2F2 Inhibitors

OR2F2 inhibitors belong to a specialized class of chemical compounds designed to interact with the OR2F2 protein, which is encoded by the OR2F2 gene. This protein is part of the olfactory receptor family, a group of cell-surface proteins that are responsible for detecting volatile compounds, which in turn are involved in the sense of smell. The science behind OR2F2 inhibitors is rooted in the intricacies of molecular biology and organic chemistry. These inhibitors function by binding to the OR2F2 receptor in a way that alters its conformation or activity, effectively modulating the receptor's ability to interact with its specific ligands or substrates. The design of OR2F2 inhibitors is a sophisticated process, often involving the identification of key binding sites on the receptor through techniques such as crystallography or computational modeling. The structural diversity of OR2F2 inhibitors is reflective of the complex nature of protein-ligand interactions. These molecules vary widely in their composition, ranging from small, organic compounds to larger, more complex molecules. They are characterized by their ability to achieve high specificity and affinity for the OR2F2 receptor, which is a result of meticulous chemical design and optimization. The development of OR2F2 inhibitors requires a deep understanding of the receptor's structure and the dynamic process by which it interacts with various molecules. Researchers involved in the synthesis and study of these inhibitors utilize a variety of chemical methods to tailor the pharmacophore-the part of the molecule that is responsible for its interaction with the receptor-to achieve the desired level of inhibition. This intricate dance between the inhibitor and the OR2F2 receptor is a testament to the delicate balance required in chemical interactions at the molecular level, emphasizing the role of precision in chemical design.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1-Octen-3-ol

3391-86-4sc-237604
25 g
$49.00
(0)

This alcohol is an olfactory inhibitor that competes for the binding site of OR2F2, as it is structurally similar to the compounds that OR2F2 typically detects. Binding to the receptor site without activating the receptor leads to decreased functional activity of OR2F2.

Copper(II) sulfate

7758-98-7sc-211133
sc-211133A
sc-211133B
100 g
500 g
1 kg
$45.00
$120.00
$185.00
3
(1)

Copper ions are known to bind to histidine residues on olfactory receptors, potentially altering the receptor's conformation. This can reduce OR2F2's ability to bind its specific odorant molecules, thereby inhibiting its functional activity.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Similar to copper, zinc ions can bind to certain amino acids within olfactory receptors, which may inhibit OR2F2 by changing its structure and preventing odorant molecule interaction.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$31.00
$61.00
$214.00
2
(1)

Eugenol is known to interact with olfactory receptors and can act as an antagonist, preventing activation of OR2F2 by its specific odorants.

Cinnamic Aldehyde

104-55-2sc-294033
sc-294033A
100 g
500 g
$102.00
$224.00
(0)

This compound can bind to olfactory receptors and, due to its structural properties, may serve as an inhibitor to OR2F2, preventing activation by its specific ligands.

Diethyl phthalate

84-66-2sc-239738
sc-239738A
25 ml
500 ml
$26.00
$32.00
(0)

This ester is known for its ability to bind to a variety of olfactory receptors, potentially acting as an inhibitor by blocking the active site of OR2F2.

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

This terpene aldehyde can bind to multiple olfactory receptors. It may inhibit OR2F2 by occupying the receptor site and preventing activation.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$105.00
$221.00
(0)

Known to have a strong odor and can competitively inhibit olfactory receptors by binding to the receptor sites, thus inhibiting the OR2F2 receptor's normal function.

(±)-Menthol

89-78-1sc-250299
sc-250299A
100 g
250 g
$38.00
$67.00
(0)

As a compound that interacts with cold-sensing ion channels, menthol may also bind to olfactory receptors, including OR2F2, and act as an inhibitor.