Date published: 2025-10-10

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OR2AG1 Activators

OR2AG1 include a variety of compounds that are primarily known for their roles as fragrance or flavor molecules. These chemicals are capable of binding to and activating OR2AG1, which is an olfactory receptor protein involved in the detection of odorant molecules. Citronellal, a molecule with a distinctive lemon scent, and eugenol, a compound found in clove oil, both bind to OR2AG1. Upon binding, these molecules cause a conformational change in OR2AG1, which leads to the activation of the receptor. Similarly, geraniol, a sweet-smelling alcohol, and menthol, known for its minty aroma, also activate OR2AG1 by attaching to the receptor, which induces a signaling cascade within the olfactory sensory neurons.

Compounds such as benzaldehyde, with its almond-like odor, and the grassy-smelling hexanal are recognized by OR2AG1. The binding of these molecules to OR2AG1 results in the receptor's activation. Phenethyl alcohol, which offers a floral fragrance, along with alpha-ionone and beta-ionone, both of which are violet-scented compounds, activate OR2AG1 in a similar fashion. Activation of OR2AG1 by these compounds leads to a series of cellular events that ultimately convey the sensation of smell. Lastly, isopentyl acetate, commonly associated with the aroma of bananas, limonene, a major component in citrus oil fragrances, and methyl salicylate, which smells like wintergreen, can also activate OR2AG1. The activation of OR2AG1 by these diverse chemicals underlies the process by which the olfactory system detects and differentiates a wide array of odorant molecules.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(±)-Citronellal

106-23-0sc-234400
100 ml
$51.00
(0)

Citronellal is known to be an odorant molecule that activates olfactory receptors. Given that OR2AG1 is an olfactory receptor, citronellal directly binds to and activates OR2AG1, leading to a change in the receptor conformation and initiation of the olfactory signaling cascade.

Eugenol

97-53-0sc-203043
sc-203043A
sc-203043B
1 g
100 g
500 g
$31.00
$61.00
$214.00
2
(1)

Eugenol is a phenylpropene, an aromatic oil that activates certain olfactory receptors. By binding to the ligand-binding site of OR2AG1, eugenol can activate the receptor, which in turn initiates a G-protein-coupled receptor signal transduction pathway specific to olfactory processes.

Geraniol

106-24-1sc-235242
sc-235242A
25 g
100 g
$44.00
$117.00
(0)

Geraniol, a monoterpenoid and an alcohol, activates olfactory receptors by binding to them. It interacts with OR2AG1 to activate it, triggering a signaling pathway that involves G-protein activation and leads to a cellular response in the olfactory sensory neurons.

(±)-Menthol

89-78-1sc-250299
sc-250299A
100 g
250 g
$38.00
$67.00
(0)

Menthol is a cyclic terpene alcohol that is known to activate certain olfactory receptors. When menthol binds to OR2AG1, it causes activation of this olfactory receptor, thereby setting off the signal transduction mechanisms in the olfactory system.

Hexanal

66-25-1sc-252885
2 ml
$26.00
(0)

Hexanal, an aliphatic aldehyde, is recognized by some olfactory receptors. It activates OR2AG1 by binding to it, which in turn triggers the olfactory signaling pathways, resulting in a sensory response.

2-Phenylethanol

60-12-8sc-238198
250 ml
$68.00
(0)

2-Phenylethanol is an aromatic alcohol that activates olfactory receptors. It binds to the OR2AG1, leading to its activation and the consequent signal transduction associated with olfactory perception.

α-Ionone

127-41-3sc-239157
100 g
$75.00
(0)

Alpha-ionone, a fragrance compound, is known to activate olfactory receptors. When alpha-ionone binds to OR2AG1, it activates the receptor, which initiates the downstream signaling events in olfactory sensory neurons.

beta-Ionone

14901-07-6sc-291976
25 ml
$83.00
(0)

Beta-ionone, similar to alpha-ionone, is another fragrance compound that activates olfactory receptors. It binds and activates OR2AG1, leading to the activation of the G-protein-coupled receptor pathway in the olfactory system.

Isopentyl acetate

123-92-2sc-250190
sc-250190A
100 ml
500 ml
$105.00
$221.00
(0)

Isopentyl acetate, also known as banana oil, activates olfactory receptors. Its interaction with OR2AG1 results in the activation of this receptor, thereby initiating the signaling mechanisms for olfactory detection.

D-Limonene

5989-27-5sc-205283
sc-205283A
100 ml
500 ml
$82.00
$126.00
3
(1)

Limonene, a prominent compound in citrus oils, activates some olfactory receptors. By binding to OR2AG1, limonene can activate this receptor, promoting the olfactory G-protein-coupled receptor signaling pathway.