OR10S1 Activators
OR10S1 can influence the protein's function through various mechanisms, primarily involving the modulation of intracellular cyclic AMP (cAMP) levels. Isoproterenol, for example, acts as a beta-adrenergic agonist, stimulating adrenergic receptors that lead to increased cAMP within cells. This elevation in cAMP is a central component in the signaling cascade that ultimately contributes to OR10S1 activation. Similarly, epinephrine and norepinephrine also engage adrenergic receptors, promoting the production of cAMP and activating OR10S1 through this common messenger molecule. In the same vein, dopamine interacts with its own receptors, potentially resulting in elevated cAMP levels and subsequent OR10S1 activation.
Forskolin serves as a direct stimulant of adenylate cyclase, thereby raising cAMP levels and activating OR10S1. This direct method bypasses receptor-ligand interactions, offering a straight path to OR10S1 activation. Another compound, 3-Isobutyl-1-methylxanthine (IBMX), and Rolipram work by inhibiting phosphodiesterases, which are enzymes responsible for cAMP breakdown. By preventing cAMP degradation, these chemicals maintain high levels of cAMP, which can activate OR10S1. Histamine operates through H2 receptors to produce a similar increase in cAMP, consequently activating OR10S1. Adenosine, engaging with A2A receptors, also follows a comparable route to raise cAMP levels and activate OR10S1. Lastly, Prostaglandin E2 (PGE2) interacts with EP receptors, which could lead to cAMP-mediated OR10S1 activation. Each of these chemicals, through varied pathways, contributes to the regulation of cAMP levels, a critical messenger in the activation of OR10S1.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $27.00 $37.00 | 5 | |
Isoproterenol, a beta-adrenergic agonist, activates adrenergic receptors leading to a cascade that can activate OR10S1 by increasing the levels of intracellular cyclic AMP (cAMP), which is known to regulate olfactory signaling pathways. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin directly stimulates adenylate cyclase, elevating cAMP levels, which can activate OR10S1 through the cAMP-dependent signaling pathway crucial for olfactory transduction processes. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $159.00 $315.00 $598.00 | 34 | |
This chemical inhibits phosphodiesterases, leading to an increase in cAMP levels, which can activate OR10S1 through enhancement of the cAMP signaling pathway. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
Epinephrine interacts with adrenergic receptors and can lead to OR10S1 activation by promoting cAMP production through G protein-coupled receptor pathways in olfactory sensory neurons. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $320.00 $475.00 | 3 | |
Norepinephrine, similar to epinephrine, binds to adrenergic receptors and can activate OR10S1 by increasing cAMP levels within the olfactory sensory neurons' signal transduction pathways. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine engages with its receptors, which may lead to an increase in cAMP through G protein signaling, potentially resulting in the activation of OR10S1 within olfactory pathways. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Histamine, through its H2 receptors, can increase cAMP levels, which might lead to the activation of OR10S1 by enhancing signal transduction in olfactory sensory neurons. | ||||||
Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Adenosine can activate A2A receptors, which in turn increases cAMP levels, potentially leading to the activation of OR10S1 as part of the olfactory signaling pathway. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
While known for DNA methylation effects, 5-Azacytidine can also raise cAMP levels under certain conditions, which might contribute to OR10S1 activation in olfactory neurons. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 engages with its EP receptors, potentially increasing cAMP in olfactory sensory neurons, which may lead to the activation of OR10S1. | ||||||