Oogenesin 3 is a protein with predicted ubiquitin ligase-substrate adaptor activity and is involved in various cellular processes, including the negative regulation of apoptosis, transcription, and the positive regulation of cell population proliferation. It is part of the Cul2-RING ubiquitin ligase complex and is primarily active in the cytoplasm. This protein plays a critical role in regulating intracellular processes and maintaining cellular homeostasis.
The functional activation of Oogenesin 3 can be influenced by several chemicals, each with specific mechanisms. Some chemicals, like 2-Mercaptoethanol and Auranofin, directly interact with the protein, stabilizing its structure and enhancing its ubiquitin ligase-substrate adaptor activity. Others, such as MG-132 and Rapamycin, indirectly affect Oogenesin 3 by modulating cellular pathways involved in protein degradation and cell proliferation, respectively. Furthermore, compounds like N-Acetylcysteine and Resveratrol support Oogenesin 3's role in protecting against oxidative stress and transcriptional regulation by preserving its structural integrity. These chemicals collectively contribute to the functional activation of Oogenesin 3, ensuring its involvement in essential cellular processes.
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