Olfr916 Activators
Olfr916 is an olfactory receptor protein, integral to the process of olfactory perception. As a member of the G-protein coupled receptors (GPCRs) family, it is responsible for detecting and differentiating a diverse range of odorant molecules. The functional activation of olfactory receptors like Olfr916 is a critical aspect of the olfactory signal transduction pathway, which converts chemical stimuli from the environment into perceptible olfactory signals. This activation begins when specific odorant molecules bind to Olfr916. The binding of these molecules causes a conformational change in the protein, initiating the signal transduction process. The specificity of the interaction between odorant molecules and Olfr916 is paramount for the selective detection of odors. This specificity is achieved through the unique binding sites of Olfr916, which are structurally compatible with certain odorant molecules. When a molecule such as isoamyl butyrate or ethyl butanoate binds to Olfr916, it induces a structural change in the receptor. This structural change triggers the activation of associated G-proteins, leading to a cascade of intracellular signaling events. These events typically involve the production of secondary messengers like cyclic AMP (cAMP) and an increase in intracellular calcium levels. These messengers amplify the olfactory signal and ultimately result in a neural response. This precise mechanism of activation allows for the accurate perception of a wide range of odors, highlighting the complexity and efficiency of the olfactory system.
Furthermore, the ability of Olfr916 to be activated by a diverse array of chemicals, each with unique structural features, exemplifies the broad specificity of olfactory receptors. This broad specificity enables the olfactory system to detect various odorant molecules, each imparting a distinct olfactory experience. The precise interaction of these chemicals with Olfr916 is crucial for the proper functioning of the olfactory system, allowing for accurate odor detection and perception. This interaction is fundamental to our sense of smell, playing an essential role in our daily interactions with the environment and contributing significantly to our overall sensory experience.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl butyrate | 106-27-4 | sc-269267 | 100 g | $67.00 | ||
Isoamyl butyrate activates Olfr916 by binding to its olfactory receptor sites, inducing a conformational change in the protein. This interaction triggers the activation of G-protein coupled signaling pathways, leading to increased intracellular calcium levels and cyclic AMP, which are vital for the functional activation and signal transduction of Olfr916, enhancing the perception of its fruity odor. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butanoate, a compound with a fruity aroma, activates Olfr916 through binding to its specific olfactory receptor sites. This binding induces a structural alteration in Olfr916, initiating the activation of G-protein coupled intracellular signaling pathways. These pathways, particularly those involving the elevation of cyclic AMP, are essential for the functional activation of Olfr916, facilitating olfactory signal transmission. | ||||||
Benzyl alcohol | 100-51-6 | sc-326216B sc-326216 sc-326216A | 250 ml 1 L 5 L | $32.00 $104.00 $416.00 | ||
Benzyl alcohol, known for its mild floral scent, activates Olfr916 by binding to its olfactory receptor sites. This binding triggers a change in the receptor's conformation, activating associated G-protein coupled signaling pathways. These pathways, including the rise in intracellular calcium and cyclic AMP levels, are important for the functional activation and proper signal transduction of Olfr916. | ||||||
Ethyl Acetate, HPLC | 141-78-6 | sc-360247 sc-360247A | 1 L 4 L | $122.00 $326.00 | ||
Ethyl acetate activates Olfr916 by binding to its olfactory receptor sites, causing a conformational change in the receptor. This alteration facilitates the activation of G-protein coupled pathways, resulting in intracellular signaling events. The increase in cyclic AMP, particularly, is essential for the functional activation of Olfr916, playing a key role in the perception of ethyl acetate's odor. | ||||||
Propyl acetate | 109-60-4 | sc-250792 | 500 ml | $20.00 | ||
Propyl acetate, a compound with a fruity odor, activates Olfr916 by interacting with its specific olfactory receptor binding sites. This interaction causes a change in the receptor's structure, triggering the activation of G-protein coupled signal transduction pathways. The activation of these pathways, especially those involving cAMP, is vital for the functional activation of Olfr916, enhancing the perception of its scent. | ||||||
Ethyl propionate | 105-37-3 | sc-214997 sc-214997A | 25 ml 500 ml | $15.00 $40.00 | ||
Ethyl propionate activates Olfr916 through molecular binding at its specific olfactory receptor sites. This binding induces a conformational change in Olfr916, leading to the activation of downstream G-protein coupled pathways. These pathways are essential for the transduction of olfactory signals mediated by Olfr916, particularly the increase in cyclic AMP levels. | ||||||
Hexyl acetate | 142-92-7 | sc-215149 sc-215149A | 25 ml 500 ml | $32.00 $57.00 | ||
Hexyl acetate, known for its sweet and fruity aroma, activates Olfr916 by binding to its olfactory receptor sites. This interaction induces a structural alteration in Olfr916, leading to the activation of G-protein coupled intracellular signaling pathways. The activation of these pathways, especially those resulting in the increase of intracellular calcium levels, is crucial for the functional activation of Olfr916. | ||||||
Butyl butyrate | 109-21-7 | sc-239439 | 250 ml | $210.00 | ||
Butyl butyrate activates Olfr916 by binding to its olfactory receptor sites, causing a conformational change. This interaction facilitates the activation of G-protein coupled pathways, leading to a series of intracellular signaling events. These events, particularly the increase in cyclic AMP, are essential for the functional activation of Olfr916, contributing to the perception of its fruity odor. | ||||||
Ethyl hexanoate | 123-66-0 | sc-235049 | 5 ml | $51.00 | ||
Ethyl hexanoate activates Olfr916 through binding to its olfactory receptor sites. This interaction induces a conformational change in the receptor, leading to the activation of G-protein coupled pathways. The subsequent intracellular signaling cascade, particularly the rise of cyclic AMP, is essential for the functional activation of Olfr916, contributing to the perception of its fruity aroma. | ||||||