Olfr870, a gene encoding a specific olfactory receptor protein, plays a pivotal role in the olfactory system, allowing organisms to perceive and differentiate a wide array of odors in their environment. The primary function of Olfr870 is to serve as a molecular detector, responsible for transducing chemical signals from the external world into neural responses within the olfactory system. This receptor, localized on the membranes of olfactory sensory neurons, serves as a molecular gateway that mediates the perception of various odorants.
Activation of Olfr870 involves intricate mechanisms that can be influenced by a variety of chemicals. These activators can act directly by binding to the receptor and inducing conformational changes that enhance its activity. Alternatively, they may stimulate downstream signaling pathways, such as the cAMP-PKA pathway or the muscarinic acetylcholine receptor pathway, leading to increased gene expression and receptor function. Some activators, like those that inhibit phosphodiesterase or promote DNA methylation, indirectly enhance Olfr870 activation by modulating intracellular processes that influence receptor activity. Overall, Olfr870 activation is a sophisticated interplay between chemical stimuli and intracellular signaling pathways, resulting in heightened olfaction sensitivity and improved receptor function. In conclusion, Olfr870 is a crucial component of the olfactory system, responsible for the perception of diverse odors in the environment. Its activation involves a complex network of interactions with various chemicals, each with its own mechanism of action. These chemicals, either by direct binding or indirect modulation of intracellular pathways, collectively contribute to the functional activation of Olfr870, ultimately facilitating the perception and discrimination of odors by the organism.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol activates Olfr870 by binding to beta-adrenergic receptors, triggering the cAMP-PKA pathway and resulting in increased gene expression and receptor activity. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP directly activates Olfr870 by mimicking cAMP, activating PKA, and enhancing receptor function, leading to increased olfaction sensitivity. | ||||||
Carbachol | 51-83-2 | sc-202092 sc-202092A sc-202092C sc-202092D sc-202092B sc-202092E | 1 g 10 g 25 g 50 g 100 g 250 g | $122.00 $281.00 $388.00 $683.00 $1428.00 $3060.00 | 12 | |
Carbachol activates Olfr870 by binding to muscarinic acetylcholine receptors, initiating intracellular signaling pathways, and enhancing gene expression and receptor function. | ||||||
Hexanal | 66-25-1 | sc-252885 | 2 ml | $27.00 | ||
Hexanal activates Olfr870 by binding to its receptor, triggering a signal cascade that amplifies receptor activity and contributes to improved olfaction sensitivity. | ||||||
Octanal | 124-13-0 | sc-250612 sc-250612A | 25 ml 100 ml | $26.00 $34.00 | ||
Octanal activates Olfr870 by directly binding to the receptor and promoting its activation, resulting in heightened olfactory perception and improved receptor function. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
3-Isobutyl-1-Methylxanthine activates Olfr870 by inhibiting phosphodiesterase, leading to increased cAMP levels, which activate PKA and enhance gene expression and receptor activity. | ||||||
1,2-Dioctanoyl-sn-glycerol | 60514-48-9 | sc-202397 sc-202397A | 10 mg 50 mg | $47.00 $254.00 | 2 | |
Diacylglycerol (DAG) activates Olfr870 by serving as a secondary messenger, stimulating protein kinase C (PKC), and enhancing gene expression and receptor function in olfaction. | ||||||
5-Bromo-2′-deoxyuridine | 59-14-3 | sc-290815 sc-290815A sc-290815B sc-290815C sc-290815D | 50 mg 250 mg 500 mg 1 g 5 g | $50.00 $79.00 $85.00 $129.00 $601.00 | ||
5-Bromo-2'-deoxyuridine activates Olfr870 by influencing DNA synthesis, ultimately leading to increased gene expression and improved receptor function in the olfactory system. | ||||||
N-Methyl-D-Aspartic acid (NMDA) | 6384-92-5 | sc-200458 sc-200458A | 50 mg 250 mg | $109.00 $369.00 | 2 | |
N-Methyl-D-Aspartate (NMDA) activates Olfr870 by binding to NMDA receptors, initiating calcium influx, and enhancing gene expression, resulting in improved olfaction sensitivity. | ||||||
Ademetionine | 29908-03-0 | sc-278677 sc-278677A | 100 mg 1 g | $184.00 $668.00 | 2 | |
S-Adenosylmethionine (SAMe) activates Olfr870 by promoting methylation of DNA, leading to increased gene expression and improved receptor function in the olfactory system. | ||||||