Olfr845 Activators
Olfr845 is a vital member of the olfactory receptor gene family, playing a central role in our sense of smell. This receptor is responsible for detecting specific odorant molecules and transmitting signals to the brain, allowing us to perceive and distinguish various scents in our environment. The activation of Olfr845 involves a range of mechanisms, including direct binding of odorant molecules to the receptor, modulation of olfactory ciliary ion channels, and influence on intracellular signaling pathways such as cAMP-PKA and MAPK. These diverse pathways lead to the functional activation of Olfr845, enabling the perception of distinct odors associated with the activating chemicals.
Understanding the intricate activation mechanisms of Olfr845 enhances our comprehension of olfaction, shedding light on how our olfactory system deciphers the complex world of scents. This knowledge contributes to the broader field of sensory perception and sensory processing, highlighting the sophistication of our sense of smell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol activates Olfr845 by modulating olfactory ciliary ion channels, increasing their activity. This enhancement results in heightened membrane depolarization and receptor activation, leading to the functional activation of Olfr845 and the perception of scents related to Eugenol. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol activates Olfr845 through the activation of the cyclic nucleotide-gated (CNG) channels in olfactory sensory neurons. It promotes channel opening, allowing an influx of cations and subsequent receptor activation. This activation pathway results in the functional activation of Olfr845, contributing to the perception of specific odors associated with Geraniol. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin activates Olfr845 by directly binding to the receptor and initiating a conformational change. This interaction leads to downstream signaling pathways being activated, ultimately resulting in the functional activation of Olfr845 and the perception of specific odors associated with Vanillin. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $28.00 | 1 | |
Anethole activates Olfr845 by acting as an allosteric modulator of the receptor, enhancing its sensitivity to odorant molecules. This modulation amplifies receptor activation and downstream signaling, ultimately leading to the functional activation of Olfr845 and the perception of specific scents. | ||||||
Isopentyl butyrate | 106-27-4 | sc-269267 | 100 g | $67.00 | ||
Isoamyl Butyrate activates Olfr845 by directly binding to the receptor, stabilizing its active conformation. This interaction prolongs receptor activation and downstream signaling, ultimately leading to the functional activation of Olfr845 and the perception of specific odors associated with Isoamyl Butyrate. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal activates Olfr845 through the modulation of olfactory ciliary ion channels. It enhances channel activity, resulting in increased membrane depolarization and receptor activation. This activation pathway leads to the functional activation of Olfr845, allowing the perception of specific odors associated with Citronellal. | ||||||
Isobutyl acetate | 110-19-0 | sc-228365 | 25 ml | $37.00 | ||
Isobutyl Acetate activates Olfr845 by influencing the cAMP-PKA pathway. It stimulates adenylyl cyclase, increasing cAMP levels, which activate protein kinase A (PKA). PKA then leads to the functional activation of Olfr845, contributing to olfactory signal transduction and odor perception. | ||||||
γ-Caprolactone | 695-06-7 | sc-251458 | 25 g | $29.00 | ||
γ-Caprolactone activates Olfr845 by directly binding to the receptor, initiating a conformational change that stabilizes its active state. This interaction prolongs receptor activation and downstream signaling, resulting in the functional activation of Olfr845 and the perception of specific odors associated with δ-Octalactone. | ||||||
2-Heptanone | 110-43-0 | sc-238060 | 1 ml | $94.00 | ||
2-Heptanone activates Olfr845 by modulating olfactory ciliary ion channels. It enhances channel opening, allowing an influx of cations and subsequent receptor activation, resulting in the functional activation of Olfr845 and the perception of specific scents associated with 2-Heptanone. | ||||||