Olfr836 Activators
Olfr836, a member of the olfactory receptor gene family, plays a pivotal role in our sense of smell. This specific receptor is responsible for detecting and discriminating various odorant molecules. When odorants bind to Olfr836, a series of events is set in motion, leading to the activation of olfactory sensory neurons and the perception of associated scents. Olfr836's activation primarily occurs through direct binding of odorants to its receptor site, which induces a conformational change and triggers signal transduction pathways, including the cAMP-PKA pathway, PLC pathway, and modulation of CNG channels. Some chemicals, such as Forskolin and Guanosine 3',5'-cyclic monophosphate, activate Olfr836 by influencing intracellular pathways, enhancing its sensitivity to odorants or inhibiting receptor antagonists. Understanding these mechanisms is crucial in unraveling the complex processes of olfaction and contributes to our comprehension of how we perceive and differentiate various scents.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $107.00 $225.00 | ||
Isopentyl acetate activates Olfr836 by binding to the receptor site, mimicking the structure of specific odorant molecules. This binding induces a conformational change in the protein, leading to signal transduction through the associated G-protein pathway and functional activation. | ||||||
beta-Ionone | 14901-07-6 | sc-291976 | 25 ml | $83.00 | ||
β-Ionone activates Olfr836 by acting as an allosteric modulator of the receptor, enhancing its sensitivity to certain odorant molecules. This modulation amplifies receptor activation and downstream signaling, ultimately resulting in the functional activation of Olfr836. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr836 by influencing intracellular calcium signaling in olfactory sensory neurons. It promotes calcium influx, which triggers the activation of Olfr836 and the transmission of olfactory signals, resulting in the functional activation of the protein. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $297.00 $577.00 | ||
L-Glutamic Acid activates Olfr836 by increasing the release of neurotransmitters, such as glutamate, at the synapses of olfactory sensory neurons. This enhanced neurotransmitter release triggers receptor activation and functional activation of Olfr836 in the olfactory system. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates Olfr836 through the mitogen-activated protein kinase (MAPK) pathway. It initiates a cascade of phosphorylation events, ultimately leading to receptor activation and functional activation of Olfr836, contributing to olfactory perception. | ||||||
2-Propanol | 67-63-0 | sc-391000C sc-391000 sc-391000B sc-391000A | 1 ml 25 ml 100 ml 500 ml | $33.00 $53.00 $63.00 $89.00 | 1 | |
2-Propanol activates Olfr836 by modulating the olfactory bulb's neuronal excitability. It enhances action potentials and synaptic transmission, ultimately leading to the activation of Olfr836 and functional activation in the olfactory system. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $47.00 $70.00 | ||
Methyl salicylate activates Olfr836 by binding to the receptor site and inducing a conformational change in the protein. This change initiates signal transduction through the associated G-protein pathway, leading to functional activation and olfactory perception. | ||||||