Olfr70 Activators
Chemical activators of Olfr70 encompass a variety of compounds that engage with the olfactory receptor, facilitating a sequence of biochemical events that culminate in its activation. Benzaldehyde, for instance, achieves this by binding to Olfr70's ligand-binding domain, which prompts a conformational change in the receptor structure, a crucial first step in olfactory signal transduction. Similarly, citral and eugenol act as activators by directly interacting with the receptor's active site, thereby inducing a cascade of intracellular responses that lead to the activation of olfactory signaling pathways. Isoamyl acetate and limonene also serve as activators by engaging directly with Olfr70, which triggers a structural change in the receptor conducive to signal propagation. This direct engagement is a common mechanism shared by other activators such as methyl salicylate, α-pinene, and β-pinene, all of which bind to Olfr70, inducing the necessary conformational rearrangements that activate the receptor and facilitate the relay of olfactory information.
Further expanding the repertoire of Olfr70 activators, vanillin and ethyl vanillin interact with the receptor, causing structural rearrangements that trigger the olfactory signaling cascade. These chemicals, by binding to the receptor, promote an active receptor state that is essential for the subsequent transmission of signals. Geraniol follows a similar activation route, with its direct binding causing a conformational shift that activates the receptor. Cinnamaldehyde, too, contributes to this array of chemical activators by binding to Olfr70's active site, inducing a change in the receptor's conformation. This action is fundamental to initiating the signal transduction pathways that underlie the sense of smell. Each of these chemicals, by virtue of their ability to activate Olfr70, plays a role in the intricate process of olfactory perception, engaging the receptor in a way that facilitates the primary function of detecting and processing olfactory signals.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral serves as an activator of Olfr70 through direct interaction with its binding site, which induces a cascade of intracellular responses culminating in receptor activation. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol activates Olfr70 by docking into its active site, which promotes the receptor's active state, facilitating the olfactory signal transduction pathway. | ||||||
Isopentyl acetate | 123-92-2 | sc-250190 sc-250190A | 100 ml 500 ml | $105.00 $221.00 | ||
Isoamyl acetate engages with Olfr70 directly, triggering a change in the receptor's structure that results in its activation and subsequent olfactory signaling. | ||||||
Dipentene | 138-86-3 | sc-252747 | 4 L | $120.00 | ||
Limonene's interaction with Olfr70 causes receptor activation by altering its conformation, which is essential for the propagation of the olfactory signal. | ||||||
Methyl Salicylate | 119-36-8 | sc-204802 sc-204802A | 250 ml 500 ml | $46.00 $69.00 | ||
Methyl salicylate activates Olfr70 by binding to it, which alters the receptor's conformation and stimulates the olfactory signal transduction mechanisms. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $51.00 $113.00 | 2 | |
α-Pinene activates Olfr70 by interacting with its ligand-binding domain, which induces a conformational change and initiates the activation of olfactory signaling pathways. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin activates Olfr70 by binding to the receptor, causing a structural rearrangement that triggers the olfactory signaling cascade. | ||||||
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl vanillin interacts with Olfr70, leading to its activation and the subsequent initiation of the olfactory signal transduction process. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $44.00 $117.00 | ||
Geraniol activates Olfr70 through direct binding, causing a conformational shift that results in the activation of olfactory signaling pathways. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamaldehyde activates Olfr70 by binding to the receptor's active site, which induces a conformational change necessary for the initiation of olfactory signal transduction. | ||||||