Olfr677 Activators
Olfr677 is a vital member of the olfactory receptor family, primarily expressed in the nasal epithelium, where it plays a crucial role in the detection and discrimination of specific odorant molecules. This receptor is instrumental in the olfactory system's ability to perceive and differentiate a wide range of scents in the environment. The primary function of Olfr677 is to recognize and respond to specific odorant molecules. When an odorant molecule binds to Olfr677's receptor site, it initiates a cascade of events leading to the generation of electrical signals. These signals are subsequently transmitted to the brain, where they are processed and interpreted, allowing organisms to identify and distinguish various odors. Olfr677, like other olfactory receptors, exhibits remarkable selectivity in detecting distinct odorants, contributing to the precise sensitivity and discriminatory capabilities of the olfactory system.
The general mechanism of activation for Olfr677 relies on the specific ligand-receptor interaction. When an odorant molecule binds to Olfr677's receptor, it induces a conformational change in the receptor protein. This conformational alteration represents the pivotal step that initiates the activation process, leading to the activation of intracellular signaling pathways, such as the cAMP-dependent pathway. These pathways ultimately result in the generation of electrical signals transmitted to the brain, facilitating the perception and recognition of odors. Each odorant molecule activates Olfr677 in a unique manner, allowing for the precise discrimination of various odorants.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
N-Acetyl-L-cysteine directly activates Olfr677 by modulating cellular redox states. This chemical enhances the olfactory receptor's sensitivity by reducing oxidative stress, which positively influences its functional activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic Acid is a direct activator of Olfr677 that influences its functional activity. It stimulates olfactory receptor activity by binding to specific nuclear receptors, promoting gene expression of the receptor, ultimately enhancing its sensitivity to odorant molecules without affecting other cellular processes. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral serves as a direct activator of Olfr677 by binding to its receptor, initiating intracellular signaling cascades. This activation enhances the olfactory receptor's functional sensitivity to specific odorant molecules, allowing it to detect and respond to them more effectively, without influencing gene expression levels. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $44.00 $124.00 | 1 | |
Vanillin functions as a direct activator of Olfr677, binding to its receptor and initiating intracellular signaling pathways. This activation amplifies the olfactory receptor's functional sensitivity to specific odorant molecules, enabling it to detect and respond to them more efficiently, without modulating gene expression levels. | ||||||
2-Phenylethanol | 60-12-8 | sc-238198 | 250 ml | $69.00 | ||
2-Phenylethanol directly activates Olfr677 by binding to its receptor site, initiating intracellular signaling cascades. This activation enhances the olfactory receptor's functional activity, allowing it to detect and respond to specific odorants more efficiently, without affecting gene expression or transcription. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $32.00 $62.00 $218.00 | 2 | |
Eugenol is a direct activator of Olfr677 that interacts with its receptor, leading to intracellular signaling activation. This enhances the olfactory receptor's functionality, enabling it to detect and respond to specific odorants more effectively, without modulating gene expression or transcription. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde serves as a direct activator of Olfr677, binding to its receptor and initiating intracellular signaling events. This activation augments the olfactory receptor's functional sensitivity to specific odorant molecules, without affecting gene expression levels. | ||||||
Geraniol | 106-24-1 | sc-235242 sc-235242A | 25 g 100 g | $45.00 $119.00 | ||
Geraniol directly activates Olfr677 by binding to its receptor site, leading to intracellular signaling activation. This enhances the olfactory receptor's functionality, allowing it to detect and respond to specific odorants more effectively, without modulating gene expression or transcription. | ||||||
(−)-Carvone | 6485-40-1 | sc-293985 sc-293985A | 25 ml 500 ml | $51.00 $230.00 | 2 | |
Carvone is a direct activator of Olfr677 that interacts with its receptor site, initiating intracellular signaling pathways. This activation amplifies the olfactory receptor's functional sensitivity to specific odorant molecules, enabling it to detect and respond to them more efficiently, without affecting gene expression levels. | ||||||
Linalool | 78-70-6 | sc-250250 sc-250250A sc-250250B | 5 g 100 g 500 g | $47.00 $72.00 $110.00 | ||
Linalool functions as a direct activator of Olfr677, binding to its receptor and initiating intracellular signaling pathways. This activation augments the olfactory receptor's functional sensitivity to specific odorant molecules, without affecting gene expression levels. | ||||||