Olfr610 Activators
Olfr610, as a member of the olfactory receptor family, plays a pivotal role in the intricate process of olfaction. These receptors are crucial in the detection and discrimination of a wide array of odorant molecules, converting chemical stimuli into neuronal signals that are processed as distinct smells. Olfr610, specifically, functions as a G-protein coupled receptor (GPCR), a class of receptors known for their diverse roles in sensory perception and various physiological processes. The activation of Olfr610, like other olfactory receptors, hinges on the binding of specific odorant molecules to the receptor. This binding is not a mere passive interaction but a critical event that induces a conformational change in Olfr610, which is essential for its activation.
The activation mechanism of Olfr610 follows the classical GPCR pathway. The initial interaction of an odorant molecule with Olfr610 alters the receptor's structure, making it conducive to interacting with G-proteins. This interaction leads to the exchange of GDP for GTP on the G-protein, activating it. The activated G-protein then disassociates into its alpha and beta-gamma subunits, which go on to activate various effector proteins. This cascade leads to the production of second messengers, such as cyclic AMP (cAMP), which play a crucial role in amplifying the signal within the olfactory sensory neuron. It is this amplified signal that eventually gets transmitted to the brain, where it is interpreted as a specific smell. The specificity of Olfr610 to certain odorant molecules underlines the remarkable ability of the olfactory system to distinguish between myriad scents. Each olfactory receptor, including Olfr610, is tuned to detect certain molecular features, contributing to the vast repertoire of smells that can be detected and interpreted by the olfactory system. The understanding of Olfr610's activation and function is vital in comprehending the broader context of olfactory perception. The intricate process of smell detection and interpretation is not just a simple binding of a molecule to a receptor but a complex series of events that translate chemical signals into a form that the brain can understand. This understanding also underscores the importance of specific molecular interactions in the activation of GPCRs, with each interaction having profound implications for the resultant physiological responses. Olfr610's role in this process is a testament to the complexity and precision of the molecular mechanisms underlying sensory perception.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
3-Ethoxy-4-hydroxybenzaldehyde | 121-32-4 | sc-238538 | 100 g | $31.00 | ||
Ethyl vanillin activates Olfr610 by directly binding to its specific ligand-binding domain. This binding induces a conformational change in Olfr610, facilitating its activation. Activation of Olfr610 triggers G-protein coupled signal transduction, leading to cellular responses typical of olfactory receptor activation. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $102.00 $224.00 | ||
Cinnamic Aldehyde interacts with Olfr610, binding to its active site. This interaction promotes a conformational change in Olfr610, which results in receptor activation. The activated Olfr610 initiates G-protein signaling cascades, culminating in olfactory signal transduction processes. | ||||||
Benzyl acetate | 140-11-4 | sc-252427 | 100 g | $29.00 | 1 | |
Benzyl acetate activates Olfr610 through direct interaction with the receptor's odorant-binding site. Upon binding, it triggers conformational changes in Olfr610, resulting in its activation. This activates downstream G-protein mediated signaling pathways involved in olfactory perception. | ||||||
Isoeugenol | 97-54-1 | sc-250186 sc-250186A | 5 g 100 g | $62.00 $52.00 | ||
Isoeugenol activates Olfr610 by binding to its odorant-binding domain. This interaction induces a structural change in Olfr610, leading to activation of the receptor. Subsequently, G-protein signaling pathways are initiated, facilitating olfactory signal transduction. | ||||||
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $27.00 | 1 | |
trans-Anethole directly interacts with Olfr610, binding to its active site. This binding promotes a structural alteration in Olfr610, resulting in receptor activation. Activation of Olfr610 leads to the initiation of G-protein mediated signaling pathways, crucial for olfactory responses. | ||||||
Vanillin | 121-33-5 | sc-251423 sc-251423A | 100 g 500 g | $43.00 $122.00 | 1 | |
Vanillin binds to and activates Olfr610 by inducing structural changes upon binding. The activated Olfr610 then initiates G-protein mediated signaling, crucial for the transmission of olfactory signals to the brain. | ||||||
(±)-Citronellal | 106-23-0 | sc-234400 | 100 ml | $51.00 | ||
Citronellal, by binding to Olfr610, activates the receptor through conformational alteration. This activation leads to the initiation of G-protein mediated intracellular signaling cascades, involved in olfactory signal transduction. | ||||||
Eugenol | 97-53-0 | sc-203043 sc-203043A sc-203043B | 1 g 100 g 500 g | $31.00 $61.00 $214.00 | 2 | |
Eugenol binds to and activates Olfr610, causing a change in receptor conformation and initiating G-protein coupled signaling cascades, which are central to the olfactory response mechanism. | ||||||