Obscurin Inhibitors
Obscurin inhibitors represent a class of chemical compounds specifically designed to modulate the activity of obscurin, a giant modular protein predominantly expressed in striated muscle tissues. Obscurin is a key regulator of sarcomeric organization and plays a crucial role in maintaining the structural integrity of muscle cells. The inhibitors within this chemical class are meticulously crafted to interfere with the function of obscurin, ultimately influencing various cellular processes associated with muscle development and contractility.
obscurin inhibitors are characterized by their ability to selectively bind to specific domains of the obscurin protein, disrupting its normal interactions with other cellular components. These compounds often exhibit a high degree of specificity, targeting regions of obscurin that are implicated in critical protein-protein interactions within the sarcomere. By doing so, obscurin inhibitors can modulate the signaling pathways and structural dynamics essential for proper muscle function. Researchers are actively investigating the molecular mechanisms through which obscurin inhibitors exert their effects, with the aim of gaining deeper insights into the intricate regulatory networks governing muscle physiology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
A potent protein kinase inhibitor, can disrupt signaling pathways that obscurin may be part of. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Inhibits ROCK, which is involved in myofibril organization, potentially affecting obscurin. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Inhibits myosin II, possibly altering the cytoskeletal dynamics associated with obscurin. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase, which could influence obscurin's role in sarcomere assembly. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Disrupts microtubule polymerization, potentially affecting obscurin's structural role. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, which might indirectly influence obscurin's cellular functions. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
Inhibits formin, possibly affecting the actin cytoskeleton and obscurin’s structural role. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments, potentially altering obscurin-related muscle structure. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Binds to actin filaments' barbed ends, potentially disrupting interactions with obscurin. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Microtubule destabilizer, might indirectly influence obscurin's role in cell structure. | ||||||