OAT3 Inhibitors
Items 1 to 10 of 15 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Novobiocin | 303-81-1 | sc-362034 sc-362034A | 5 mg 25 mg | $96.00 $355.00 | ||
Novobiocin exhibits unique interactions with the OAT3 transporter, characterized by its ability to alter substrate binding dynamics. Its structural conformation facilitates specific hydrogen bonding and hydrophobic interactions, enhancing its affinity for the transporter. This modulation affects the kinetics of organic anion transport, providing insights into the regulatory mechanisms of renal excretion. The compound's distinct physicochemical properties contribute to its selective inhibition profile, influencing transport efficiency in cellular systems. | ||||||
Probenecid-d14 | sc-219644 | 1 mg | $273.00 | |||
Probenecid-d14 demonstrates intriguing interactions with the OAT3 transporter, primarily through its isotopic labeling, which allows for enhanced tracking in metabolic studies. Its unique structure promotes specific electrostatic interactions, influencing the conformational dynamics of the transporter. This compound's kinetic behavior reveals insights into the transport mechanisms of organic anions, while its distinct isotopic signature aids in elucidating metabolic pathways and transporter specificity in experimental settings. | ||||||
Probenecid | 57-66-9 | sc-202773 sc-202773A sc-202773B sc-202773C | 1 g 5 g 25 g 100 g | $27.00 $38.00 $98.00 $272.00 | 28 | |
Inhibits renal tubular secretion, potentially affecting OAT3 function in drug excretion. | ||||||
Steviol | 471-80-7 | sc-253605A sc-253605 | 10 mg 50 mg | $192.00 $860.00 | ||
Steviol exhibits notable interactions with the OAT3 transporter, characterized by its ability to form hydrogen bonds that stabilize the transporter’s conformation. This compound's unique steric properties facilitate selective binding, influencing the transport kinetics of organic anions. Additionally, its hydrophobic regions enhance membrane permeability, providing insights into the dynamics of substrate recognition and transport efficiency, thereby enriching our understanding of organic anion transport mechanisms. | ||||||
Furosemide | 54-31-9 | sc-203961 | 50 mg | $40.00 | ||
Loop diuretic, can influence renal ion transport, potentially impacting OAT3-mediated anion transport. | ||||||
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $28.00 $37.00 | 18 | |
NSAID, may affect renal anion transport, potentially inhibiting OAT3 function. | ||||||
Ibuprofen | 15687-27-1 | sc-200534 sc-200534A | 1 g 5 g | $52.00 $86.00 | 6 | |
NSAID, can influence renal drug transport, potentially affecting OAT3's anion transport activity. | ||||||
Cimetidine | 51481-61-9 | sc-202996 sc-202996A | 5 g 10 g | $62.00 $86.00 | 1 | |
Histamine H2-receptor antagonist, may affect renal excretion pathways, potentially impacting OAT3. | ||||||
Ketoprofen | 22071-15-4 | sc-205359 sc-205359A | 5 g 25 g | $93.00 $308.00 | 2 | |
NSAID, can alter renal anion transport, potentially affecting OAT3 function. | ||||||
Diclofenac acid | 15307-86-5 | sc-357332 sc-357332A | 5 g 25 g | $107.00 $292.00 | 5 | |
NSAID, potentially affects renal excretion mechanisms, impacting OAT3 activity. | ||||||