Date published: 2026-4-30

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NTR1 Inhibitors

NTR1 inhibitors comprise a diverse group of chemicals that selectively modulate the activity of neurotensin receptor 1 (NTR1), a G protein-coupled receptor involved in mediating the effects of neurotensin. SR 142948A inhibits NTR1 by binding to its receptor site, blocking the interaction with neurotensin. This disrupts the NTR1 signaling pathway, inhibiting downstream events associated with neurotensin binding and modulating cellular processes influenced by NTR1 activation. Similarly, PD 90780 interferes with the receptor-ligand interaction, blocking neurotensin binding and subsequently inhibiting NTR1-mediated signaling cascades. Levocabastine and Quinpirole act as NTR1 inhibitors by disrupting the receptor-ligand interaction, impeding neurotensin binding and inhibiting downstream signaling events. Levocabastine specifically interferes with NTR1 activation, modulating cellular processes influenced by neurotensin. Nilotinib indirectly inhibits NTR1 by interfering with signaling pathways associated with neurotensin-induced events, disrupting downstream cascades linked to NTR1 activation and inhibiting cellular processes influenced by neurotensin. The compounds SR 142948, PD 151746, Nitroquazone, and SR 48692B function as NTR1 inhibitors by binding to the receptor site and blocking the interaction with neurotensin. These inhibitors disrupt the NTR1 signaling pathway, leading to the inhibition of downstream events associated with neurotensin binding and the modulation of cellular processes influenced by NTR1 activation. NVP-AEW541 inhibits NTR1 indirectly by interfering with signaling pathways associated with neurotensin-induced events. As an insulin-like growth factor-1 receptor (IGF-1R) inhibitor, NVP-AEW541 disrupts downstream cascades linked to NTR1 activation, inhibiting cellular processes influenced by neurotensin. Collectively, these inhibitors offer valuable tools for researchers to selectively modulate NTR1 activity, contributing to a deeper understanding of the regulatory mechanisms and cellular functions associated with neurotensin receptor 1.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SR 48692

146362-70-1sc-363290
sc-363290A
sc-363290B
sc-363290C
sc-363290D
5 mg
25 mg
100 mg
500 mg
1 g
$159.00
$605.00
$2374.00
$10710.00
$21410.00
2
(0)

SR 48692 inhibits NTR1 by binding to its receptor site, blocking the interaction with neurotensin. This compound disrupts the NTR1 signaling pathway, leading to the inhibition of downstream events associated with neurotensin binding and subsequent modulation of cellular processes influenced by NTR1 activation.

Nilotinib

641571-10-0sc-202245
sc-202245A
10 mg
25 mg
$209.00
$413.00
9
(1)

Nilotinib inhibits NTR1 indirectly by interfering with signaling pathways associated with neurotensin-induced events. This tyrosine kinase inhibitor disrupts downstream signaling cascades linked to NTR1 activation, leading to the inhibition of cellular processes influenced by neurotensin.

(−)-Quinpirole hydrochloride

85798-08-9sc-253339
10 mg
$141.00
1
(1)

Quinpirole inhibits NTR1 by interfering with its receptor-ligand interaction, preventing the binding of neurotensin. This compound disrupts the NTR1 signaling pathway, resulting in the inhibition of downstream events associated with neurotensin binding and the modulation of cellular processes influenced by NTR1 activation.

SR 142948

184162-64-9sc-204297
sc-204297A
1 mg
10 mg
$138.00
$292.00
(1)

SR 142948B inhibits NTR1 by binding to its receptor site, blocking the interaction with neurotensin. This compound disrupts the NTR1 signaling pathway, leading to the inhibition of downstream events associated with neurotensin binding and subsequent modulation of cellular processes influenced by NTR1 activation.

NVP-AEW541

475489-16-8sc-507395
5 mg
$285.00
(0)

NVP-AEW541 inhibits NTR1 indirectly by interfering with signaling pathways associated with neurotensin-induced events. This insulin-like growth factor-1 receptor (IGF-1R) inhibitor disrupts downstream signaling cascades linked to NTR1 activation, leading to the inhibition of cellular processes influenced by neurotensin.

PD 151746

179461-52-0sc-222134
5 mg
$196.00
3
(1)

PD 151746 inhibits NTR1 by interfering with its receptor-ligand interaction, preventing the binding of neurotensin. This compound disrupts the NTR1 signaling pathway, resulting in the inhibition of downstream events associated with neurotensin binding and the modulation of cellular processes influenced by NTR1 activation.

Nitrofurazone

59-87-0sc-212400
sc-212400A
100 mg
100 g
$89.00
$129.00
(0)

Nitrofurazone inhibits NTR1 by interfering with its receptor-ligand interaction, preventing the binding of neurotensin. This compound disrupts the NTR1 signaling pathway, resulting in the inhibition of downstream events associated with neurotensin binding and the modulation of cellular processes influenced by NTR1 activation.