NMDA Activators
Santa Cruz Biotechnology now offers a broad range of NMDA Activators. Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. NMDA Activators offered by Santa Cruz activate NMDA and, in some cases, other neurotransmission and neural development related proteins. View detailed NMDA Activator specifications, including NMDA Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 21 to 29 of 29 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
DL-Cysteine hydrochloride | 10318-18-0 | sc-255126 sc-255126A | 5 g 10 g | $114.00 $193.00 | ||
DL-Cysteine hydrochloride serves as a notable NMDA receptor modulator, primarily through its role in redox biology. Its thiol group can form mixed disulfides, altering protein interactions and influencing receptor sensitivity. This compound also engages in competitive binding with neurotransmitters, affecting ion channel permeability. Furthermore, its solubility in aqueous environments enhances its bioavailability, allowing for dynamic interactions within neural pathways and synaptic plasticity. | ||||||
L-CCG-IV | 117857-95-1 | sc-203098 | 1 mg | $209.00 | ||
L-CCG-IV is a selective NMDA receptor modulator that exhibits unique binding characteristics, particularly at the glycine site. Its structural conformation allows for enhanced receptor activation, influencing calcium ion influx and synaptic signaling. The compound's ability to stabilize receptor complexes contributes to its distinct kinetic profile, promoting prolonged receptor engagement. Additionally, L-CCG-IV's hydrophilic nature facilitates effective interactions within cellular environments, impacting neuronal communication and plasticity. | ||||||
Ibotenic acid | 2552-55-8 | sc-200449 sc-200449A | 1 mg 5 mg | $118.00 $412.00 | 1 | |
A powerful excitotoxin that acts as an agonist at NMDA receptors, mimicking the action of L-glutamic acid. | ||||||
2,3-Pyridinedicarboxylic acid | 339155-13-4 | sc-288387 sc-288387A | 25 g 100 g | $26.00 $69.00 | ||
2,3-Pyridinedicarboxylic acid acts as a modulator of NMDA receptor activity, showcasing unique interactions with the receptor's allosteric sites. Its dual carboxylic acid groups enable specific hydrogen bonding, enhancing receptor affinity and influencing downstream signaling pathways. The compound's capacity to alter ion channel kinetics promotes a nuanced response in synaptic transmission. Furthermore, its polar nature aids in solubility, facilitating effective cellular uptake and interaction with membrane proteins. | ||||||
L-Aspartic acid | 56-84-8 | sc-472377A sc-472377 sc-472377B | 25 g 100 g 500 g | $39.00 $32.00 $47.00 | ||
Can function as an agonist at the NMDA receptor site. | ||||||
cis-ACPD | 39026-63-6 | sc-202102 | 5 mg | $60.00 | ||
Cis-ACPD is a potent agonist of the metabotropic glutamate receptors, exhibiting unique binding characteristics that enhance receptor activation. Its structural conformation allows for selective interactions with specific receptor subtypes, influencing intracellular signaling cascades. The compound's ability to modulate calcium ion influx through distinct pathways contributes to its role in synaptic plasticity. Additionally, its hydrophilic properties facilitate effective membrane permeability, promoting dynamic cellular responses. | ||||||
CIQ | 486427-17-2 | sc-361150 sc-361150A | 10 mg 50 mg | $145.00 $645.00 | ||
CIQ acts as a selective NMDA receptor modulator, characterized by its unique ability to stabilize the receptor's open state, enhancing ion channel conductance. Its distinct molecular interactions promote a conformational shift that favors calcium ion influx, crucial for synaptic transmission. The compound's kinetic profile reveals rapid binding and unbinding rates, allowing for precise temporal control of neuronal excitability. Furthermore, its lipophilic nature aids in membrane integration, influencing cellular signaling dynamics. | ||||||
DL-Glutamic acid monohydrate | 19285-83-7 | sc-255128 sc-255128A sc-255128B sc-255128C | 10 g 25 g 100 g 1 kg | $46.00 $53.00 $96.00 $550.00 | ||
DL-Glutamic acid monohydrate serves as a potent NMDA receptor agonist, facilitating neurotransmission through its ability to mimic the natural neurotransmitter glutamate. Its structural conformation allows for effective binding to the receptor, promoting a significant increase in calcium and sodium ion permeability. The compound exhibits unique solubility characteristics, enhancing its diffusion across cellular membranes, which plays a critical role in modulating synaptic plasticity and neuronal communication. | ||||||
L-Glutamic acid monosodium salt | 142-47-2 | sc-215218 sc-215218A | 100 g 500 g | $42.00 $66.00 | 1 | |
L-Glutamic acid monosodium salt acts as a selective NMDA receptor modulator, engaging in specific ionic interactions that enhance synaptic signaling. Its unique ionic form increases solubility in aqueous environments, promoting rapid diffusion and effective receptor binding. This compound influences intracellular signaling pathways by altering calcium influx, which is crucial for synaptic strength and plasticity. Its distinct molecular structure allows for versatile interactions within neural networks, impacting overall excitatory neurotransmission. | ||||||