NMDA Activators
Santa Cruz Biotechnology now offers a broad range of NMDA Activators. Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. NMDA Activators offered by Santa Cruz activate NMDA and, in some cases, other neurotransmission and neural development related proteins. View detailed NMDA Activator specifications, including NMDA Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 11 to 20 of 29 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(R)-(+)-HA-966 | 123931-04-4 | sc-361303 | 5 mg | $95.00 | ||
(R)-(+)-HA-966 is a selective NMDA receptor antagonist that exhibits unique stereochemical properties, enhancing its binding affinity. Its chiral configuration allows for specific interactions with receptor subtypes, influencing conformational changes that modulate ion flow. This compound also impacts downstream signaling cascades, potentially altering synaptic plasticity. Its distinct kinetic profile suggests a rapid onset of action, making it a subject of interest in neurobiological research. | ||||||
D-Cycloserine | 68-41-7 | sc-221470 sc-221470A sc-221470B sc-221470C | 200 mg 1 g 5 g 25 g | $27.00 $75.00 $139.00 $520.00 | 4 | |
D-Cycloserine acts as a partial agonist at NMDA receptors, engaging in unique interactions that facilitate calcium ion influx. Its structural conformation allows for selective binding to the receptor's glycine site, influencing receptor activation dynamics. This compound exhibits a distinctive modulation of synaptic transmission, potentially affecting neuroplasticity. Additionally, its interaction with other neurotransmitter systems may contribute to its complex behavioral effects in neural pathways. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Spermidine is a polyamine that plays a crucial role in cellular processes by modulating NMDA receptor activity. It enhances receptor function through allosteric interactions, promoting calcium ion permeability and influencing synaptic plasticity. Its unique ability to stabilize RNA structures and interact with various cellular signaling pathways underscores its importance in cellular growth and differentiation. Spermidine's dynamic role in modulating neurotransmission highlights its multifaceted impact on neuronal function. | ||||||
Pregnenolone sulfate sodium salt | 1852-38-6 | sc-301609 | 50 mg | $97.00 | 2 | |
This neurosteroid modulates NMDA receptor activity by enhancing its response to glutamate and glycine. | ||||||
Spermine, Tetrahydrochloride | 306-67-2 | sc-202817 | 5 g | $166.00 | ||
Spermine, Tetrahydrochloride is a polyamine that significantly influences NMDA receptor dynamics by acting as a potent modulator. It facilitates receptor activation through specific binding interactions, enhancing ion channel conductance and promoting neuronal excitability. Its unique structural features allow it to engage in hydrogen bonding and electrostatic interactions, which are critical for stabilizing receptor conformations. Additionally, spermine's role in cellular signaling pathways contributes to its impact on cellular homeostasis and growth regulation. | ||||||
Spermidine trihydrochloride | 334-50-9 | sc-360822 sc-360822A sc-360822B sc-360822C sc-360822D | 1 g 5 g 25 g 100 g 250 g | $45.00 $138.00 $465.00 $1200.00 $2823.00 | ||
Spermidine trihydrochloride is a polyamine that plays a crucial role in modulating NMDA receptor activity. Its unique structure allows for specific interactions with receptor sites, influencing ion permeability and synaptic plasticity. The compound's ability to form transient complexes with receptor subunits enhances signaling efficiency. Furthermore, spermidine's involvement in cellular processes, such as autophagy and gene expression regulation, underscores its significance in maintaining cellular integrity and function. | ||||||
Homoquinolinic acid | 490-75-5 | sc-200456 sc-200456A | 5 mg 25 mg | $117.00 $587.00 | ||
Homoquinolinic acid is a potent NMDA receptor modulator characterized by its unique ability to interact with specific binding sites, influencing receptor conformation and ion channel dynamics. Its structural features facilitate distinct hydrogen bonding and hydrophobic interactions, which can alter the kinetics of receptor activation. Additionally, the compound's role in calcium ion flux regulation highlights its potential impact on neuronal excitability and synaptic transmission, contributing to complex signaling pathways in the nervous system. | ||||||
L-Cysteinesulfinic acid | 1115-65-7 | sc-203620 sc-203620A sc-203620B sc-203620C | 100 mg 250 mg 500 mg 1 g | $200.00 $450.00 $600.00 $1020.00 | ||
L-Cysteinesulfinic acid serves as a notable NMDA receptor modulator, distinguished by its capacity to form unique disulfide bonds that influence receptor stability and function. Its molecular structure allows for specific electrostatic interactions, enhancing binding affinity and altering receptor kinetics. Furthermore, it plays a role in redox signaling pathways, potentially affecting neurotransmitter release and synaptic plasticity, thereby contributing to intricate neural communication networks. | ||||||
Quinolinic acid | 89-00-9 | sc-203226 | 1 g | $31.00 | 7 | |
A metabolite of the kynurenine pathway that acts as an agonist at the NMDA receptor. | ||||||
DL-Cysteine | 3374-22-9 | sc-255125 | 10 g | $52.00 | ||
DL-Cysteine exhibits intriguing properties as an NMDA receptor modulator, characterized by its ability to participate in thiol-disulfide exchange reactions. This feature enables it to influence the redox state of the receptor environment, potentially modulating receptor conformation and activity. Additionally, its unique side chain facilitates interactions with metal ions, which can further impact receptor dynamics and signaling pathways, contributing to the complexity of synaptic transmission. | ||||||