nm23-H4 Activators

The nm23-H4 activators embody a diverse range of compounds that predominantly influence mitochondrial function and cellular energy metabolism. For instance, they are recognized as activators of AMPK. Activation of AMPK enhances mitochondrial biogenesis and function, thereby potentially impacting the activity of nm23-H4, situated within the mitochondria. Activators are also implicated in mitochondrial function but through alternative means. They serve as alternative electron carriers within the mitochondrial electron transport chain.

On the other hand, nm23-H4 activators exert their influence by enhancing NAD+ levels or activating SIRT1, a known regulator of cellular energy metabolism and mitochondrial function. In particular, they are recognized as SIRT1 activators, and their activation of SIRT1 can potentially modulate nm23-H4. Activators of this class are known to stimulate mitochondrial biogenesis, which may indirectly affect nm23-H4. Lastly, activators could indirectly influence nm23-H4 through its impact on mitochondrial function.